⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27520889 | 0.97 | TSHR (0.38) | — | |
| SCHEMBL3296573 | 0.93 | TSHR (0.40) | — | |
| SCHEMBL3767964 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL502449 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL153637 | 0.85 | TSHR (0.46) | — | |
| SCHEMBL9745743 | 0.82 | — | — | |
| Bromide SCHEMBL20500234 | 0.81 | TSHR (0.43) | — | |
| Hydrochloric Acid SCHEMBL2140796 | 0.81 | TSHR (0.43) | — | |
| Iodide SCHEMBL20500143 | 0.81 | TSHR (0.43) | — | |
| Fluoride SCHEMBL27639896 | 0.81 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546987-C | The preparation method of DL-nebivolol and hydrochloride thereof | XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) | 2009-10-07 | — | — | CN | claimed |
| CN-1683355-A | Process for preparing DL-nebivolol and its hydrochloride | XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) | 2005-10-19 | — | — | CN | claimed |
| CN-111936505-B | Tertiary alkyl-substituted polycyclic aromatic compounds and uses thereof | 学校法人关西学院 | 2024-07-02 | — | — | CN | disclosed |
| CN-118239965-A | Polycyclic aromatic compound, polymer thereof, material for organic device, use of the same, organic electroluminescent element, and use of the same | 国立大学法人京都大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-118239964-A | Polycyclic aromatic compound, polymer compound, material for organic device, organic electroluminescent element, display device, and lighting device | 国立大学法人京都大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-118221707-A | Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device | 国立大学法人京都大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-118221706-A | Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device | 国立大学法人京都大学 | 2024-06-21 | — | — | CN | disclosed |
| WO-2024128314-A1 | POLYCYCLIC AROMATIC COMPOUND | 国立大学法人京都大学 | 2024-06-20 | — | — | WO | disclosed |
| CN-118108749-A | Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device | 国立大学法人京都大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-118027048-A | Nitrogen-containing heteropolycyclic compound, material, element, display device, and lighting device | 爱思开新材料捷恩智株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-113412265-B | Polycyclic aromatic compounds | 学校法人关西学院 | 2024-05-03 | — | — | CN | disclosed |
| EP-1732566-A2 | 6-AZAINDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097129-A2 | 6-AZAINDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-10-20 | — | — | WO | disclosed |
| CN-1683355-A | Process for preparing DL-nebivolol and its hydrochloride | XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) | 2005-10-19 | — | — | CN | disclosed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| EP-0373216-A1 | CEPHALOSPORIN COMPOUNDS OR THEIR SALTS, PROCESS FOR THEIR PREPARATION, AND PARMACEUTICAL COMPOSITIONS | TEIJIN LIMITED (JP) | 1990-06-20 | — | — | EP | disclosed |
| US-4892962-A | FROM ALLYL DIFLUOROACETATES AND A MONOCHLORO=SILANE, ADDITION POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0347459-A1 | CEPHALOSPORIN COMPOUNDS OR THEIR SALTS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS | TEIJIN LIMITED (JP) | 1989-12-27 | — | — | EP | disclosed |
| US-4692536-A | Process for the preparation of hemiaminals, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0012760-B1 | PHARMACEUTICALLY ACTIVE 6,9-THIAPROSTACYCLIN ANALOGS AND DERIVATIVES THEREOF | Research Corporation (US) | 1983-10-19 | — | — | EP | disclosed |