SCHEMBL329659

SCHEMBL329659

O=S(=O)(O)c1cnccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.43
KDM4E B2RXH2 6/20 0.41
HCAR2 Q8TDS4 1/20 0.41
ADORA3 P0DMS8 1/20 0.40
TSHR P16473 1/20 0.40
MC4R P32245 1/20 0.40
ADRA1A P35348 1/20 0.40
MC3R P41968 1/20 0.40
SLC40A1 Q9NP59 1/20 0.39
NLRP3 Q96P20 1/20 0.38
HSP90AA1 P07900 1/20 0.37
NAMPT P43490 3/20 0.36
ABCC9 O60706 1/20 0.36
ABCC8 Q09428 1/20 0.36
KCNJ11 Q14654 1/20 0.36
KCNJ8 Q15842 1/20 0.36
BAZ2B Q9UIF8 1/20 0.35
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10716049 0.98 NAPRT (0.42) NAPRTKDM4EHCAR2ADORA3TSHR
SCHEMBL8155865 0.98 NAPRT (0.42) NAPRTKDM4EHCAR2ADORA3TSHR
Hydrochloric Acid SCHEMBL27947207 0.98 NAPRT (0.42) NAPRTKDM4EHCAR2ADORA3TSHR
SCHEMBL7835984 0.80 SLC40A1 (0.41) NAPRTKDM4EHCAR2ADORA3TSHR
SCHEMBL329658 0.78 SLC40A1 (0.40) NAPRTKDM4EHCAR2ADORA3TSHR
SCHEMBL11561904 0.76 KDM4E (0.39) NAPRTKDM4ETSHRALDH1A1SMN1; SMN2
SCHEMBL1076499 0.76 CA12 (0.43) NAPRTKDM4EHCAR2ADORA3TSHR
SCHEMBL3155945 0.76 SLC40A1 (0.39) NAPRTKDM4EHCAR2ADORA3TSHR
SCHEMBL8230218 0.76 SLC40A1 (0.46) NAPRTKDM4EHCAR2ADORA3TSHR
SCHEMBL10716052 0.74 SLC40A1 (0.38) NAPRTKDM4EHCAR2ADORA3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200360562-A1 ADHESION LAYER BONDED TO AN ACTIVATED SURFACE THE TRUSTEES OF PRINCETON UNIVERSITY 2020-11-19 US claimed
US-20070009592-A1 IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM UNIVERSITEIT GENT (BE) 2007-01-11 US claimed
EP-4298167-B1 PROCESS FOR PREPARING AN ANTIMICROBIAL COATING COMPOSITION, ANTIMICROBIAL COATING COMPOSITION AND USE THEREOF TO CONFER ANTIMICROBIAL PROPERTIES TO THE SURFACE OF A SUBSTRATE ENI SPA (IT) 2025-10-01 EP disclosed
US-20240166896-A1 PROCESS FOR PREPARING AN ANTIMICROBIAL COATING COMPOSITION, ANTIMICROBIAL COATING COMPOSITION AND USE THEREOF TO CONFER ANTIMICROBIAL PROPERTIES TO THE SURFACE OF A SUBSTRATE ENI S.P.A. (IT) 2024-05-23 US disclosed
EP-4366733-A1 TETRAHYDROPYRAZOLOPYRIDINE-ANALOG LIGANDS OF NLRX1 AND USES THEREOF LANDOS BIOPHARMA, INC. (US) 2024-05-15 EP disclosed
CN-112859523-B Polyimide positive photoresist composition 台湾永光化学工业股份有限公司 2024-04-26 CN disclosed
CN-117597361-A Heterodimeric antibodies and antigen-binding fragments thereof 成都恩沐生物科技有限公司 2024-02-23 CN disclosed
EP-3927427-B1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME NIMMUNE BIOPHARMA INC (US) 2024-02-07 EP disclosed
EP-4298167-A1 PROCESS FOR PREPARING AN ANTIMICROBIAL COATING COMPOSITION, ANTIMICROBIAL COATING COMPOSITION AND USE THEREOF TO CONFER ANTIMICROBIAL PROPERTIES TO THE SURFACE OF A SUBSTRATE ENI S.p.A. (IT) 2024-01-03 EP disclosed
US-20230357744-A1 ENGINEERED TRYPTOPHAN DECARBOXYLASES AND USES THEREOF FOR SYNTHESIZING TRYPTAMINE ANALOGS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-11-09 US disclosed
CN-116940641-A Method for producing an antimicrobial coating composition, antimicrobial coating composition and use thereof for imparting antimicrobial properties to a substrate surface 埃尼股份公司 2023-10-24 CN disclosed
EP-0358400-B1 Improvements in or relating to polymeric compounds DU PONT (US) 1993-11-10 EP disclosed
US-5236966-A POLYMERIC MATERIALS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1993-08-17 US disclosed
US-5227276-A NEGATIVE-WORKING RADIATION-SENSITIVE MIXTURE, AND RADIATION-SENSITIVE RECORDING MATERIAL PRODUCED WITH THIS MIXTURE HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
EP-0489068-A1 POLYMERIC MATERIALS. BRITISH TECH GROUP (GB) 1992-06-10 EP disclosed
WO-1991002763-A1 POLYMERIC MATERIALS BRITISH TECHNOLOGY GROUP PLC (GB) 1991-03-07 WO disclosed
EP-0358400-A2 Improvements in or relating to polymeric compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-14 EP disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
US-4638005-A ELECTRON CARRIERS IN THE PHOTOENZYMATIC PRODUCTION OF HYDROGEN AND AMMONIA THE COCA-COLA COMPANY 1987-01-20 US disclosed
US-4496647-A Treatment of image-forming laminated plate TORAY INDUSTRIES, INC. (JP) 1985-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200360562-A1 ADHESION LAYER BONDED TO AN ACTIVATED SURFACE EPCAM, ICAM1, ITGAL NAPRT 2389/4885KDM4E 3864/4885HCAR2 754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.