Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sulfosalicylic. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.93 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.93 |
| ▸ | HPGD | P15428 | 2/20 | 0.93 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfosalicylic SCHEMBL6536711 | 1.00 | ALDH1A1 (0.93) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL8769448 | 0.98 | ALDH1A1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL8592874 | 0.98 | ALDH1A1 (0.89) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL29034690 | 0.98 | ALDH1A1 (0.89) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL6717073 | 0.98 | ALDH1A1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL34766 | 0.98 | ALDH1A1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL29364125 | 0.98 | ALDH1A1 (0.96) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL25356542 | 0.96 | ALDH1A1 (0.93) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL818713 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Sulfosalicylic SCHEMBL8030761 | 0.96 | ALDH1A1 (0.93) | ALDH1A1HSD17B10KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 844 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912911-B | Conductive polypyrrole/nano cellulose composite film material and preparation method thereof | 东华大学 | 2022-12-02 | — | — | CN | claimed |
| CN-112053859-B | Preparation method of fabric-based flexible planar micro supercapacitor | 盐城工学院 | 2021-12-03 | — | — | CN | claimed |
| CN-112053859-A | Preparation method of fabric-based flexible planar micro supercapacitor | 盐城工学院 | 2020-12-08 | — | — | CN | claimed |
| CN-110017114-A | A kind of well killing method and well killing fluid of novel well workover | 杨凌单色生物科技有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-109836512-A | A kind of novel β-CD Gemini surface active agent is the clean fracturing fluid of thickening agent | 西南石油大学 | 2019-06-04 | — | — | CN | claimed |
| CN-109758872-A | A kind of composite chelate iron desulfurizing agent and preparation method thereof | 浙江佳运能源技术有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-109516510-A | A kind of nickel cobalt manganese hydroxide of special micro-nano structure and preparation method thereof | 华友新能源科技（衢州）有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-109467167-A | A kind of method of heavy metal in removal stainless steel acid cleaning waste water | 上海大学 | 2019-03-15 | — | — | CN | claimed |
| CN-109289557-A | A kind of decoloration film and its preparation method and application | 中国科学院过程工程研究所 | 2019-02-01 | — | — | CN | claimed |
| CN-108946827-A | A kind of ultra-small grain size nickel cobalt manganese hydroxide and preparation method thereof | 华友新能源科技（衢州）有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-102004090-A | Design of off-on fluorescent molecular probe for selective recognition of Cd2+ | FANG LI | 2011-04-06 | — | — | CN | claimed |
| CN-1184225-C | Tetraphosphine quatorphosphonium salt, its preparing process, and two-step tetraphosphine medicine kit and its application | UNIV BEIJING NORMAL (CN) | 2005-01-12 | — | — | CN | claimed |
| CN-1142322-C | Chemically polishing method for stainless steel | 太原师范学院 | 2004-03-17 | — | — | CN | claimed |
| CN-1126603-C | Process for preparing selective disproportionation catalyst of toluene | CHINA PETROCHEMICAL CORP (CN) | 2003-11-05 | — | — | CN | claimed |
| CN-1418820-A | Nano Titanium dioxide, prepn. process and use thereof | UNIV WUHAN (CN) | 2003-05-21 | — | — | CN | claimed |
| CN-1389464-A | Blue modifier and its prepn. process and application | LU ZHONGYUAN (CN) | 2003-01-08 | — | — | CN | claimed |
| CN-1373241-A | Chemically polishing method for stainless steel | TAIYUAN NORMAL COLLEGE (CN) | 2002-10-09 | — | — | CN | claimed |
| CN-1340486-A | Process for preparing selective disproportionation catalyst of toluene | CHINA PETROCHEMICAL CORP (CN) | 2002-03-20 | — | — | CN | claimed |
| CN-1064986-C | Composition for cleaning and etching electronic display and substrate | LEE KI WON (KR) | 2001-04-25 | — | — | CN | claimed |
| CN-1137517-A | Preparing reagent grade sulfosalicylic acid and its sodium salt by industrial product epuration | CHEMICAL INST OF HENAN PROV AC (CN) | 1996-12-11 | — | — | CN | claimed |