⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765939 | 0.70 | TNF (0.37) | — | |
| SCHEMBL329830 | 0.70 | — | — | |
| SCHEMBL29497464 | 0.67 | ADORA2A (0.57) | — | |
| SCHEMBL343400 | 0.67 | ADORA2A (0.57) | — | |
| SCHEMBL17837 | 0.67 | — | — | |
| SCHEMBL709685 | 0.67 | AXL (1.00) | — | |
| SCHEMBL29523425 | 0.67 | — | — | |
| SCHEMBL1996526 | 0.65 | — | — | |
| Methane SCHEMBL14738986 | 0.65 | AXL (0.95) | — | |
| Potassium SCHEMBL30760557 | 0.65 | AXL (0.95) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 540 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070278-A | Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof | 标新生物医药科技(上海)有限公司 | 2026-05-19 | — | — | CN | claimed |
| WO-2025101944-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2025-05-15 | — | — | WO | claimed |
| WO-2025082069-A1 | COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN | 中国海洋大学 | 2025-04-24 | — | — | WO | claimed |
| US-20250099442-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES INC | 2025-03-27 | — | — | US | claimed |
| EP-4444721-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2024-10-16 | — | — | EP | claimed |
| CN-112218631-B | Heterocyclic inhibitors of ATR kinase | 德州大学系统董事会 | 2023-12-22 | — | — | CN | claimed |
| WO-2023107722-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | claimed |
| EP-3765008-B1 | HETEROCYCLIC INHIBITORS OF ATR KINASE | UNIV TEXAS (US) | 2023-06-07 | — | — | EP | claimed |
| EP-3814357-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC Therapeutics, Inc. (US) | 2021-05-05 | — | — | EP | claimed |
| US-10894052-B2 | Heterocyclic inhibitors of ATR kinase | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-01-19 | — | — | US | claimed |
| CN-112218631-A | Heterocyclic inhibitors of ATR kinase | 德州大学系统董事会 | 2021-01-12 | — | — | CN | claimed |
| US-20190282584-A1 | HETEROCYCLIC INHIBITORS OF ATR KINASE | ARTIOS PHARMA LIMITED (GB) | 2019-09-19 | — | — | US | claimed |
| US-10093678-B2 | Azaspiro derivatives as TRPM8 antagonists | RAQUALIA PHARMA INC. (JP) | 2018-10-09 | — | — | US | claimed |
| EP-0534323-B1 | Process for the preparation of high chloride tabular grain emulsions (II) | EASTMAN KODAK CO (US) | 1997-05-14 | — | — | EP | claimed |
| US-5389509-A | Surface treatment of grains with an organonitrogen compound | EASTMAN KODAK COMPANY (US) | 1995-02-14 | — | — | US | claimed |
| EP-0534323-A1 | Process for the preparation of high chloride tabular grain emulsions (II) | EASTMAN KODAK COMPANY (US) | 1993-03-31 | — | — | EP | claimed |
| US-5178997-A | A fused N-heterocyclic compound as a grain growth modifier; materials handling | EASTMAN KODAK COMPANY (US) | 1993-01-12 | — | — | US | claimed |
| EP-4027995-B1 | HPK1 ANTAGONISTS AND USES THEREOF | NIMBUS SATURN INC (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-0534323-A1 | Process for the preparation of high chloride tabular grain emulsions (II) | EASTMAN KODAK COMPANY (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5178997-A | A fused N-heterocyclic compound as a grain growth modifier; materials handling | EASTMAN KODAK COMPANY (US) | 1993-01-12 | — | — | US | disclosed |