SCHEMBL3298253

SCHEMBL3298253

Nc1cc(N)cc(NC(=O)c2cc(N)cc(N)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
LMNA P02545 1/20 0.52
POLB P06746 1/20 0.52
APEX1 P27695 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SNCA P37840 1/20 0.52
THRB P10828 1/20 0.46
TOP1 P11387 2/20 0.45
TOP2A P11388 2/20 0.45
TOP2B Q02880 2/20 0.45
PTGS1 P23219 5/20 0.45
NQO2 P16083 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
DDX3X O00571 1/20 0.41
KCNK3 O14649 1/20 0.41
KCNK9 Q9NPC2 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12540695 0.89 MEN1 (0.67) PKMMEN1KMT2ALMNAPOLB
SCHEMBL6364543 0.86 KMT2A (0.53) PKMMEN1KMT2ALMNAPOLB
SCHEMBL10042212 0.86 L3MBTL1 (0.58) PKMMEN1KMT2ALMNAPOLB
SCHEMBL27586874 0.85 POLB (0.74) PKMMEN1KMT2ALMNAPOLB
SCHEMBL9318389 0.85 POLB (0.74) PKMMEN1KMT2ALMNAPOLB
SCHEMBL11508480 0.85 PTGS1 (0.65) MEN1KMT2ATOP1TOP2ATOP2B
SCHEMBL14407440 0.84 PTPN1 (0.58) PKMMEN1KMT2ALMNAPOLB
SCHEMBL11583304 0.84 L3MBTL1 (0.65) PKMMEN1KMT2ALMNAPOLB
SCHEMBL19752757 0.83 SNCA (0.42) PKMMEN1KMT2ALMNAPOLB
SCHEMBL11581414 0.82 L3MBTL1 (0.62) PKMMEN1KMT2ALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070039874-A1 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY 2007-02-22 US claimed
EP-0211633-B2 Semipermeable composite membrane TORAY INDUSTRIES (JP) 1995-05-31 EP claimed
US-10207230-B2 Composite membrane with support comprising poly(phenylene ether) and amphilphilic polymer; method of making; and separation module thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-02-19 US disclosed
EP-3137200-A1 COMPOSITE MEMBRANE WITH SUPPORT COMPRISING POLY(PHENYLENE ETHER) AND AMPHILPHILIC POLYMER; METHOD OF MAKING; AND SEPARATION MODULE THEREOF SABIC Global Technologies B.V. (NL) 2017-03-08 EP disclosed
US-20170043301-A1 COMPOSITE MEMBRANE WITH SUPPORT COMPRISING POLY(PHENYLENE ETHER) AND AMPHILPHILIC POLYMER; METHOD OF MAKING; AND SEPARATION MODULE THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-16 US disclosed
EP-2788108-A1 MEMBRANE, WATER TREATMENT SYSTEM, AND METHOD OF MAKING General Electric Company (US) 2014-10-15 EP disclosed
CN-104010717-A Membrane, Water Treatment System, And Method Of Making GEN ELECTRIC 2014-08-27 CN disclosed
WO-2013085657-A1 MEMBRANE, WATER TREATMENT SYSTEM, AND METHOD OF MAKING GENERAL ELECTRIC COMPANY (US) 2013-06-13 WO disclosed
US-20130146530-A1 MEMBRANE, WATER TREATMENT SYSTEM, AND METHOD OF MAKING GENERAL ELECTRIC COMPANY (US) 2013-06-13 US disclosed
US-7727434-B2 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY (US) 2010-06-01 US disclosed
US-20080312349-A1 METHOD OF MAKING AND USING MEMBRANE GENERAL ELECTRIC COMPANY (US) 2008-12-18 US disclosed
US-20080203012-A1 MEMBRANE, APPARATUS, AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed
US-20080207822-A1 COMPOSITION AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed
WO-2008103599-A2 COMPOSITION, ITS USE IN THE PREPARATION OF MEMBRANES, AND SYSTEMS COMPRISING THE MEMBRANES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-28 WO disclosed
US-20070039874-A1 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY 2007-02-22 US disclosed
EP-0211633-B2 Semipermeable composite membrane TORAY INDUSTRIES (JP) 1995-05-31 EP disclosed
US-4761234-A CROSSLINKED POLYAMIDES FOR SEMIPERMEABLE MEMBRANES TORAY INDUSTRIES, INC. (JP) 1988-08-02 US disclosed
EP-0211633-A2 Semipermeable composite membrane TORAY INDUSTRIES, INC. (JP) 1987-02-25 EP disclosed