Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239614 | 0.81 | TSHR (0.42) | ADORA2AABL1EGFRSRCABL2 | |
| SCHEMBL9404581 | 0.81 | HPGD (0.47) | KMT2AADORA2AALDH1A1HPGDBCL2L1 | |
| SCHEMBL28180007 | 0.79 | ALDH1A1 (0.35) | KMT2AALDH1A1HPGDNOTUM | |
| SCHEMBL27979361 | 0.79 | ALDH1A1 (0.35) | KMT2AALDH1A1HPGDNOTUM | |
| SCHEMBL14562749 | 0.79 | ALDH1A1 (0.35) | KMT2AALDH1A1HPGDNOTUM | |
| SCHEMBL7996476 | 0.79 | ALDH1A1 (0.35) | KMT2AALDH1A1HPGDNOTUM | |
| SCHEMBL2517442 | 0.79 | ALDH1A1 (0.35) | KMT2AALDH1A1HPGDNOTUM | |
| SCHEMBL28807262 | 0.79 | ALDH1A1 (0.35) | KMT2AALDH1A1HPGDNOTUM | |
| SCHEMBL8349665 | 0.78 | ALDH1A1 (0.47) | ADORA2ATDO2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28121946 | 0.78 | ALDH1A1 (0.47) | ADORA2ATDO2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494694-B1 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | DEVELOGEN ISRAEL LTD (IL) | 2013-05-08 | — | — | EP | disclosed |
| US-7700717-B2 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | DEVELOGEN ISRAEL LTD. (IL) | 2010-04-20 | — | — | US | disclosed |
| US-20050090429-A1 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | TEL HASHOMER - MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD. (IL) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090429-A1 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | SSTR4, SSTR1, SSTR3 | PDCD1 1217/4885CD274 1563/4885DPP4 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.