Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052402 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL4299028 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL329900 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL3725588 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL12468506 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL1537604 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL13817962 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL5036319 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL7644054 | 0.99 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL1536344 | 0.99 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105861585-A | Method for splitting hepatitis c NS3 enzyme inhibitor drug intermediate through sphingomonasaquatilis | 北京化工大学 | 2016-08-17 | — | — | CN | claimed |
| WO-2023044171-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-03-23 | — | — | WO | disclosed |
| CN-105861585-B | A method of hepatitis C NS3 enzyme inhibitor medicine intermediate is split using Sphingomonas | 北京化工大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-105861585-B | A method of hepatitis C NS3 enzyme inhibitor medicine intermediate is split using Sphingomonas | 北京化工大学 | 2019-08-02 | — | — | CN | disclosed |
| EP-2496556-B1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2018-12-26 | — | — | EP | disclosed |
| US-9636375-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-02 | — | — | US | disclosed |
| US-9636375-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-02 | — | — | US | disclosed |
| EP-2813500-B1 | Intermediates for the preparation of hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2813500-B1 | Intermediates for the preparation of hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-08-17 | — | — | EP | disclosed |
| CN-105861585-A | Method for splitting hepatitis c NS3 enzyme inhibitor drug intermediate through sphingomonasaquatilis | 北京化工大学 | 2016-08-17 | — | — | CN | disclosed |
| WO-2005046712-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-05-26 | — | — | WO | disclosed |
| EP-1505963-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2004094452-A2 | MACROCYCLIC ISOQUINOLINE PEPTIDE INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |
| WO-2004094452-A2 | MACROCYCLIC ISOQUINOLINE PEPTIDE INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |
| US-20040106559-A1 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-06-03 | — | — | US | disclosed |
| WO-2003099274-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003099274-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003053349-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |
| EP-1105413-A2 | HEPATITIS C INHIBITOR TRI-PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000009543-A2 | HEPATITIS C INHIBITOR TRI-PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106559-A1 | Hepatitis C virus inhibitors | HAVCR2, HCCS, RNASE1 | SMN1; SMN2 4722/4885ALDH1A1 512/4885KMT2A 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.