Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.52 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Syringol SCHEMBL156388 | 0.83 | KDM4E (0.80) | KDM4EMAPTTP53LMNACYP3A4 | |
| Syringol SCHEMBL8986496 | 0.80 | KDM4E (0.76) | KDM4EMAPTTP53LMNACYP3A4 | |
| Syringol SCHEMBL6049240 | 0.80 | KDM4E (0.76) | KDM4EMAPTTP53LMNACYP3A4 | |
| Syringol SCHEMBL7610366 | 0.80 | KDM4E (0.76) | KDM4EMAPTTP53LMNACYP3A4 | |
| SCHEMBL18840034 | 0.80 | ALDH1A1 (0.47) | KDM4EMAPTTP53LMNACYP3A4 | |
| SCHEMBL1686802 | 0.80 | — | — | |
| 3-Methoxycatechol SCHEMBL67332 | 0.78 | TP53 (1.00) | KDM4EMAPTTP53LMNACYP3A4 | |
| 3-Methoxycatechol SCHEMBL29477155 | 0.78 | TP53 (1.00) | KDM4EMAPTTP53LMNACYP3A4 | |
| Syringol SCHEMBL3328072 | 0.76 | KDM4E (0.70) | KDM4EMAPTTP53LMNACYP3A4 | |
| Syringol SCHEMBL20564590 | 0.76 | KDM4E (0.70) | KDM4EMAPTTP53LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
| CN-116731028-B | Tetracyclic lactam compound and preparation method thereof | 五邑大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-116731028-A | Tetracyclic lactam compound and preparation method thereof | 五邑大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116731028-A | Tetracyclic lactam compound and preparation method thereof | 五邑大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-108997282-B | Arylbenzofuran derivatives having alpha-glucosidase inhibitory activity | 安徽工程大学 | 2022-04-29 | — | — | CN | disclosed |
| WO-2022045033-A1 | TETRACYCLIC COMPOUND HAVING DIHYDROBENZOFURAN RING OR DIHYDROBENZOPYRAN RING, AND FRAGRANCE MATERIAL COMPOSITION CONTAINING SAME | 高砂香料工業株式会社 | 2022-03-03 | — | — | WO | disclosed |
| CN-108997282-A | Arylbenzofuran analog derivative with alpha-glucosaccharase enzyme inhibition activity | 安徽工程大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105492437-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2018-05-11 | — | — | CN | disclosed |
| US-9505739-B2 | Spiropyrrolidine beta-secretase inhibitors for the treatment of alzheimer's disease | MERCK SHARP & DOHME CORP. (US) | 2016-11-29 | — | — | US | disclosed |
| WO-2004073598-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A.U. (ES) | 2004-09-02 | — | — | WO | disclosed |
| US-6716987-B1 | PHOSPHODIESTERASE IV INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| WO-2002102803-A1 | TOTAL SYNTHESIS OF GALANTHAMINE, ANALOGUES AND DERIVATIVES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2002-12-27 | — | — | WO | disclosed |
| US-20020128290-A1 | DERIVATIVES OF BENZOFURAN OR BENZODIOXOLE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-0287909-B1 | AMYLOIDOSIS AND ALZHEIMER'S DISEASE DIAGNOSTIC ASSAY AND REAGENTS THEREFOR | SALUTAR, INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5039511-A | Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5008099-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4933156-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0287909-A1 | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1988-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128290-A1 | DERIVATIVES OF BENZOFURAN OR BENZODIOXOLE | CBR1, CBR3, CYC1 | KDM4E 3975/4885MAPT 3600/4885TP53 2008/4885 |
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | KDM4E 3880/4885MAPT 4709/4885TP53 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.