Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777998 | 0.85 | ATM (0.66) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6862889 | 0.82 | HDAC3 (0.51) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3298906 | 0.80 | KMT2A (0.54) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5755449 | 0.78 | GAA (0.53) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5755454 | 0.78 | GAA (0.53) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3298283 | 0.73 | KMT2A (0.45) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5783922 | 0.71 | HRH2 (0.53) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5783538 | 0.71 | HRH2 (0.53) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27456766 | 0.70 | ATM (0.70) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14916078 | 0.70 | HDAC4 (0.41) | ATMHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093883-A1 | Hydroxamic Esters as Photoinitiators | LAMBERTI SPA (IT) | 2010-04-15 | — | — | US | disclosed |
| EP-2121323-A1 | HYDROXAMIC ESTERS AS PHOTOINITIATORS | Lamberti Spa (IT) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008104436-A1 | HYDROXAMIC ESTERS AS PHOTOINITIATORS | LAMBERTI SPA (IT) | 2008-09-04 | — | — | WO | disclosed |