SCHEMBL3298906

SCHEMBL3298906

CN(O)C(=O)C1c2ccccc2Oc2ccc(S)cc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.54
MEN1 O00255 5/20 0.54
USP2 O75604 1/20 0.54
TSHR P16473 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
CHRM2 P08172 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
ATM Q13315 1/20 0.45
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3298283 0.81 KMT2A (0.45) KMT2AMEN1USP2TSHRSMN1; SMN2
SCHEMBL3299243 0.80 ATM (0.50) KMT2AMEN1USP2TSHRSMN1; SMN2
SCHEMBL27714231 0.68 KMT2A (0.58) KMT2AMEN1USP2TSHRSMN1; SMN2
SCHEMBL1128337 0.67 ATM (0.66) KMT2AMEN1USP2TSHRSMN1; SMN2
SCHEMBL8819216 0.67 KMT2A (0.60) KMT2AMEN1USP2TSHRSMN1; SMN2
SCHEMBL8820711 0.67 KMT2A (0.64) KMT2AMEN1USP2TSHRSMN1; SMN2
SCHEMBL27456766 0.67 ATM (0.70) KMT2AMEN1USP2TSHRSMN1; SMN2
SCHEMBL8820477 0.66 KMT2A (0.67) KMT2AMEN1USP2TSHRSMN1; SMN2
SCHEMBL156372 0.65 ATM (0.68) KMT2AMEN1USP2TSHRSMN1; SMN2
Xanthene Carboxylic Acid SCHEMBL30011680 0.65 ATM (0.68) KMT2AMEN1USP2TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093883-A1 Hydroxamic Esters as Photoinitiators LAMBERTI SPA (IT) 2010-04-15 US disclosed
EP-2121323-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS Lamberti Spa (IT) 2009-11-25 EP disclosed
WO-2008104436-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS LAMBERTI SPA (IT) 2008-09-04 WO disclosed