Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958246 | 0.89 | CYP2A6 (0.52) | CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B2 | |
| SCHEMBL9958676 | 0.85 | CYP19A1 (0.50) | CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B2 | |
| SCHEMBL28581879 | 0.85 | NOTUM (0.56) | PIK3CAMKNK1KIF11DYRK1A | |
| SCHEMBL9958975 | 0.85 | NOTUM (0.56) | PIK3CAMKNK1KIF11DYRK1A | |
| SCHEMBL27955545 | 0.85 | MAPT (0.48) | CYP19A1KIF11DYRK1A | |
| SCHEMBL19817613 | 0.77 | CYP2A6 (0.65) | CYP2A6CYP3A4ALDH1A1CYP1A2PIK3CA | |
| SCHEMBL320526 | 0.77 | CYP2A6 (0.79) | CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B2 | |
| SCHEMBL29626674 | 0.77 | CYP2A6 (0.79) | CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B2 | |
| SCHEMBL9958537 | 0.77 | CYP2A6 (0.54) | CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B2 | |
| SCHEMBL24492814 | 0.76 | CYP2A6 (0.62) | CYP2A6CYP3A4ALDH1A1CYP1A2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741352-B2 | KCNQ channel modulating compounds and their pharmaceutical use | NEUROSEARCH A/S (DK) | 2010-06-22 | — | — | US | disclosed |
| US-20060173058-A1 | Kcnq channel modulating compounds and their pharmaceutical use | NEUROSEARCH A/S (DK) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173058-A1 | Kcnq channel modulating compounds and their pharmaceutical use | KCNQ1, KCNQ2, KCNQ5 | CYP2A6 1621/4885CYP3A4 1211/4885ALDH1A1 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.