Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28581879 | 1.00 | NOTUM (0.56) | NOTUMMKNK1PIK3CAPRMT6MAPT | |
| SCHEMBL27955545 | 0.92 | MAPT (0.48) | NOTUMPRMT6MAPTLMNAPRKCI | |
| SCHEMBL1451004 | 0.88 | ALDH1A1 (0.43) | NOTUMMAPTLMNAHSD17B10KDM4E | |
| SCHEMBL8938017 | 0.86 | ALOX5 (0.41) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1535844 | 0.86 | ALDH1A1 (0.38) | NOTUMMAPTLMNANPC1RAB9A | |
| SCHEMBL3299454 | 0.85 | CYP2A6 (0.47) | MKNK1PIK3CAKIF11DYRK1A | |
| SCHEMBL18221938 | 0.82 | ALDH1A1 (0.38) | NOTUMMAPTLMNANPC1RAB9A | |
| SCHEMBL9958676 | 0.82 | CYP19A1 (0.50) | MKNK1MAPTLMNANPC1RAB9A | |
| SCHEMBL9958246 | 0.82 | CYP2A6 (0.52) | MKNK1PRMT6MAPTLMNANPC1 | |
| SCHEMBL15067523 | 0.82 | ALDH1A1 (0.45) | NOTUMMAPTLMNAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311844-B | Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component | 东曹株式会社 | 2021-07-20 | — | — | CN | disclosed |
| US-9624193-B2 | Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component | TOSOH CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| CN-102574813-B | Cyclic azine derivatives, process for producing the same, and organic electroluminescent element containing the same as constituent | TOSOH CORP. (JP) | 2016-03-30 | — | — | CN | disclosed |
| US-20150329544-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | TOSOH CORPORATION (JP) | 2015-11-19 | — | — | US | disclosed |
| US-9120773-B2 | Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component | TOSOH CORPORATION (JP) | 2015-09-01 | — | — | US | disclosed |
| EP-2818462-A1 | Cyclic azine derivatives, processes for producing these, and organic electrolumiscent element containing these as component | TOSOH CORPORATION (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20120214993-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | SAGAMI CHEMICAL RESEARCH INSTITUTE, (JP) | 2012-08-23 | — | — | US | disclosed |
| CN-102574813-A | Cyclic azine derivatives, process for producing the same, and organic electroluminescent element containing the same as constituent | TOSOH CORP | 2012-07-11 | — | — | CN | disclosed |
| EP-2468731-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | Tosoh Corporation (JP) | 2012-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329544-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | CPNE4, EPB41, AZI2 | NOTUM 2918/4885MKNK1 3550/4885PIK3CA 857/4885 |
| US-20120214993-A1 | CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT | CPNE4, EPB41, AZI2 | NOTUM 2918/4885MKNK1 3550/4885PIK3CA 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.