SCHEMBL3299672

SCHEMBL3299672

CCCCOc1ccc([SiH](O[SiH](c2ccc(OCCCC)c(CC)c2)c2ccc(OCCCC)c(CC)c2)c2ccc(OCCCC)c(CC)c2)cc1CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
ATM Q13315 2/20 0.39
HPGD P15428 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 2/20 0.37
CNR2 P34972 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
TLR8 Q9NR97 1/20 0.37
NPSR1 Q6W5P4 3/20 0.37
GAA P10253 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3300325 0.87 MAPT (0.39) MAPTL3MBTL1ATMHPGDCYP1A2
SCHEMBL3297896 0.85 CYP1A2 (0.41) MAPTL3MBTL1ATMCYP1A2CYP2C9
SCHEMBL3301588 0.85 MAPT (0.43) MAPTL3MBTL1HPGDCYP2C19SMN1; SMN2
SCHEMBL3296233 0.82 ESR1 (0.48) MAPTL3MBTL1CYP1A2CYP2C9CYP2C19
SCHEMBL3296118 0.80 TAAR1 (0.42) L3MBTL1MEN1KMT2AALDH1A1KDM4E
SCHEMBL3298706 0.79 TSHR (0.41) MAPTL3MBTL1CYP1A2CYP2C9CYP2C19
SCHEMBL3297582 0.78 THRA (0.43) CYP1A2CYP2C9CYP2C19SMN1; SMN2LMNA
SCHEMBL11345868 0.76 MAPT (0.57) MAPTL3MBTL1ATMHPGDCYP1A2
SCHEMBL3298810 0.75 HTT (0.40) L3MBTL1CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL3299978 0.75 GRIN2D (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 MAPT 2685/4885L3MBTL1 1173/4885ATM 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.