SCHEMBL3300274

SCHEMBL3300274

CCOc1ccc([SiH](O[SiH](c2ccc(OCC)cc2CC)c2ccc(OCC)cc2CC)c2ccc(OCC)cc2CC)c(CC)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.45
ALDH1A1 P00352 4/20 0.41
MAPT P10636 3/20 0.41
HSD17B10 Q99714 3/20 0.41
HPGD P15428 2/20 0.41
ESR2 Q92731 1/20 0.41
CYP1A2 P05177 3/20 0.39
KDM4E B2RXH2 2/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
LTA4H P09960 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3302669 0.86 L3MBTL1 (0.43) ALDH1A1MAPTKDM4ECA12CA1
SCHEMBL3297405 0.86 NQO1 (0.45) NQO1ALDH1A1MAPTHSD17B10HPGD
SCHEMBL3301676 0.84 HSD17B10 (0.41) ALDH1A1HSD17B10
SCHEMBL3296971 0.80 KDM4E (0.47) NQO1ALDH1A1MAPTHSD17B10HPGD
SCHEMBL3296786 0.80 NQO1 (0.46) NQO1ALDH1A1MAPTHSD17B10HPGD
SCHEMBL3297866 0.78 NQO1 (0.48) NQO1ALDH1A1MAPTHSD17B10HPGD
SCHEMBL7083444 0.77 NQO1 (0.56) NQO1ALDH1A1MAPTHSD17B10HPGD
SCHEMBL3301870 0.76 NQO1 (0.46) NQO1ALDH1A1MAPTHSD17B10HPGD
SCHEMBL3296595 0.76 NQO1 (0.42) NQO1ALDH1A1MAPTHSD17B10HPGD
SCHEMBL3300291 0.76 POLB (0.38) ALDH1A1MAPTCYP1A2LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 NQO1 3910/4885ALDH1A1 1865/4885MAPT 2685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.