Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300349 | 1.00 | HTR2A (0.37) | HTR2ASLC6A4CYP3A4ADRA2AKMT2A | |
| SCHEMBL3316914 | 0.84 | CYP3A4 (0.37) | SLC6A4CYP3A4ADRA2AKMT2ALMNA | |
| SCHEMBL3324011 | 0.82 | CYP1A2 (0.35) | HTR2ASLC6A4CYP3A4ADRA2AKMT2A | |
| SCHEMBL3324009 | 0.82 | CYP1A2 (0.35) | HTR2ASLC6A4CYP3A4ADRA2AKMT2A | |
| SCHEMBL6491226 | 0.79 | CYP3A4 (0.37) | CYP3A4ADRA2ALMNAL3MBTL1THRB | |
| SCHEMBL6491231 | 0.79 | CYP3A4 (0.37) | CYP3A4ADRA2ALMNAL3MBTL1THRB | |
| SCHEMBL6491363 | 0.79 | SCN9A (0.40) | HTR2ASLC6A4KMT2AKCNH2 | |
| SCHEMBL6491366 | 0.79 | SCN9A (0.40) | HTR2ASLC6A4KMT2AKCNH2 | |
| SCHEMBL15022625 | 0.78 | F10 (0.36) | SLC6A4CYP3A4ADRA2AL3MBTL1THRB | |
| SCHEMBL15022483 | 0.78 | TEAD1 (0.42) | CYP3A4KMT2ALMNAGFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120558-B1 | 3,4-Disubstituted phenoxyphenylamidine derivatives and their use as fungicides | BAYER IP GMBH (DE) | 2016-02-10 | — | — | EP | disclosed |
| US-8080688-B2 | 3, 4-disubstituted phenoxyphenylamidines and use thereof as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20100093533-A1 | 3, 4-DISUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCEINCE AG (DE) | 2010-04-15 | — | — | US | disclosed |
| EP-2120558-A2 | 3,4-DISUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110281-A2 | 3,4-DISUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-18 | — | — | WO | disclosed |
| EP-1969935-A1 | 3.4-disubstituted phenoxy phenylamidines and their use as fungicides | Bayer CropScience AG (DE) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093533-A1 | 3, 4-DISUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | DDT, PAH, CYP4B1 | HTR2A 1521/4885SLC6A4 1014/4885CYP3A4 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.