Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324011 | 1.00 | CYP1A2 (0.35) | CYP1A2CYP2C19SLC6A4HTR2ACYP3A4 | |
| SCHEMBL3316914 | 0.92 | CYP3A4 (0.37) | CYP1A2CYP2C19SLC6A4CYP3A4ADRA2A | |
| SCHEMBL3326015 | 0.88 | SLC6A4 (0.34) | SLC6A4HTR2ACYP3A4ADRA2AALDH1A1 | |
| SCHEMBL3326013 | 0.88 | SLC6A4 (0.34) | SLC6A4HTR2ACYP3A4ADRA2AALDH1A1 | |
| SCHEMBL3300347 | 0.82 | HTR2A (0.37) | CYP1A2CYP2C19SLC6A4HTR2ACYP3A4 | |
| SCHEMBL3300349 | 0.82 | HTR2A (0.37) | CYP1A2CYP2C19SLC6A4HTR2ACYP3A4 | |
| SCHEMBL22176888 | 0.80 | TTR (0.43) | SLC6A4CYP3A4ADRA2AALDH1A1MEN1 | |
| SCHEMBL2685505 | 0.79 | SMN1; SMN2 (0.36) | SLC6A4HTR2ACYP3A4ADRA2AMAPT | |
| SCHEMBL15649015 | 0.79 | SMN1; SMN2 (0.36) | SLC6A4HTR2ACYP3A4ADRA2AMAPT | |
| SCHEMBL2685504 | 0.79 | SMN1; SMN2 (0.36) | SLC6A4HTR2ACYP3A4ADRA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299302-B2 | 4-Cycloalkyl or 4-substituted phenoxyphenylamidines and use thereof as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20100120615-A1 | 4-CYCLOALKYL OR 4-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120615-A1 | 4-CYCLOALKYL OR 4-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | DDT, CYP4B1, PAH | CYP1A2 13/4885CYP2C19 10/4885SLC6A4 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.