⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317505 | 0.77 | — | — | |
| SCHEMBL16176823 | 0.73 | — | — | |
| SCHEMBL294039 | 0.73 | — | — | |
| SCHEMBL6772032 | 0.73 | — | — | |
| SCHEMBL1804311 | 0.69 | — | — | |
| SCHEMBL4782993 | 0.69 | — | — | |
| SCHEMBL1560322 | 0.69 | — | — | |
| SCHEMBL28151184 | 0.67 | — | — | |
| SCHEMBL18774917 | 0.65 | TSHR (0.43) | — | |
| SCHEMBL27672980 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161277-B1 | Asymmetric synthesis of peptides | UNIV READING (GB) | 2013-04-10 | — | — | EP | disclosed |
| US-8399612-B2 | Asymmetric synthesis of peptides | UNIVERSITY OF READING (GB) | 2013-03-19 | — | — | US | disclosed |
| US-8318798-B2 | Therapeutic agent for neurodegenerative disease | NATIONAL UNIVERSITY CORPORATION HOKKALDO UNIVERSITY (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20120190816-A9 | ASYMMETRIC SYNTHESIS OF PEPTIDES | UNIVERSITY OF READING | 2012-07-26 | — | — | US | disclosed |
| EP-2407167-A2 | Therapeutic agent for neurodegenerative disease | National University Corporation Hokkaido University (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20110275784-A1 | ASYMMETRIC SYNTHESIS OF PEPTIDES | UNIVERSITY OF READING | 2011-11-10 | — | — | US | disclosed |
| US-8044173-B2 | Asymmetric synthesis of peptides | UNIVERSITY OF READING (GB) | 2011-10-25 | — | — | US | disclosed |
| EP-2161277-A2 | Asymmetric synthesis of peptides | University of Reading (GB) | 2010-03-10 | — | — | EP | disclosed |
| US-20090233872-A1 | Therapeutic Agent for Neurodegenerative Disease | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20080281075-A1 | ASYMMETRIC SYNTHESIS OF PEPTIDES | UNIVERSITY OF READING (GB) | 2008-11-13 | — | — | US | disclosed |
| EP-1974732-A1 | THERAPEUTIC AGENT FOR NEURODEGENERATIVE DISEASE | National University Corporation Hokkaido University (JP) | 2008-10-01 | — | — | EP | disclosed |
| EP-1937708-A1 | ASYMMETRIC SYNTHESIS OF PEPTIDES | THE UNIVERSITY OF READING (GB) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007031698-A1 | ASYMMETRIC SYNTHESIS OF PEPTIDES | UNIVERSITY OF READING (GB) | 2007-03-22 | — | — | WO | disclosed |
| US-6210901-B1 | MODIFIED HEPATITIS C VIRUS AMINO ACID SEQUENCE WHICH BINDS TO AN ANTIBODY; FOR SCREENING BLOOD SAMPLES | ROCHE DIAGNOSTICS GMBH (DE) | 2001-04-03 | — | — | US | disclosed |