⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16176823 | 1.00 | — | — | |
| SCHEMBL294039 | 1.00 | — | — | |
| SCHEMBL2185815 | 0.79 | PTGS1 (0.48) | — | |
| SCHEMBL2154512 | 0.78 | — | — | |
| SCHEMBL27604246 | 0.73 | — | — | |
| SCHEMBL330043 | 0.73 | — | — | |
| SCHEMBL360350 | 0.73 | — | — | |
| SCHEMBL3628671 | 0.73 | — | — | |
| SCHEMBL28567598 | 0.71 | PTGS1 (0.40) | — | |
| SCHEMBL170745 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040197293-A1 | Anionic polyurethanes with elastic property | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | claimed |
| US-5403750-A | Polyetherurethanes modified with amine, mercpto or hydroxyl functional groups | W. R. GRACE & CO.-CONN. (US) | 1995-04-04 | — | — | US | claimed |
| WO-2010014943-A2 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICS, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| US-20040197293-A1 | Anionic polyurethanes with elastic property | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-0510393-B1 | Biocompatible, low protein adsorption affinity matrix | GRACE W R & CO (US) | 1995-10-04 | — | — | EP | disclosed |
| US-5403750-A | Polyetherurethanes modified with amine, mercpto or hydroxyl functional groups | W. R. GRACE & CO.-CONN. (US) | 1995-04-04 | — | — | US | disclosed |
| EP-0367362-B1 | Chemically modified hydrophilic prepolymers and polymers | GRACE W R & CO (US) | 1994-06-15 | — | — | EP | disclosed |
| EP-0510393-A1 | Biocompatible, low protein adsorption affinity matrix | W.R. Grace & Co.-Conn. (US) | 1992-10-28 | — | — | EP | disclosed |
| EP-0386614-A1 | Cell growth enhancers and/or antibody production stimulators comprising chemically modified hydrophilic polyurea-urethane prepolymers and polymers | W.R. Grace & Co.-Conn. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4940737-A | Biocompatible polyurethane three-dimensional hydrogels or foams | W. R. GRACE & CO.-CONN (US) | 1990-07-10 | — | — | US | disclosed |
| US-4929706-A | POLYOXYETHYLENE PREPOLYMERS | W. R. GRACE & CO.-CONN. (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0367362-A2 | Chemically modified hydrophilic prepolymers and polymers | W.R. Grace & Co.-Conn. (US) | 1990-05-09 | — | — | EP | disclosed |