Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394746 | 1.00 | PDE4B (0.38) | PDE4BGRIK1GRIA2GPR119PDE4A | |
| SCHEMBL3394535 | 0.90 | GRIK1 (0.42) | GRIK1GRIA2GPR119AR | |
| SCHEMBL5640115 | 0.90 | GPR119 (0.36) | GRIK1GRIA2GPR119UCHL1AR | |
| SCHEMBL3303900 | 0.90 | GPR119 (0.36) | GRIK1GRIA2GPR119UCHL1AR | |
| SCHEMBL3391573 | 0.90 | GPR119 (0.36) | GRIK1GRIA2GPR119UCHL1AR | |
| SCHEMBL3303727 | 0.90 | GRIK1 (0.42) | GRIK1GRIA2GPR119AR | |
| SCHEMBL3395739 | 0.86 | GRIK1 (0.37) | GRIK1GRIA2GPR119UCHL1AR | |
| SCHEMBL3394767 | 0.83 | GRIK1 (0.42) | PDE4BGRIK1GRIA2GPR119AR | |
| SCHEMBL3303581 | 0.82 | GPR119 (0.37) | PDE4BGRIK1GRIA2GPR119AR | |
| SCHEMBL3303609 | 0.82 | GPR119 (0.39) | PDE4BGRIK1GRIA2GPR119AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | MARTINEZ-PEREZ JOSE ANTONIO | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | SLC1A2, SLC1A1, GRIN1 | PDE4B 3213/4885GRIK1 8/4885GRIA2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.