Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295453 | 0.93 | MCHR1 (0.34) | MCHR1HRH3HRH4CTSLCTSB | |
| SCHEMBL3294284 | 0.91 | MCHR1 (0.36) | MCHR1HRH3HRH4CTSLCTSB | |
| SCHEMBL3295259 | 0.88 | MCHR1 (0.35) | MCHR1HRH3HRH4CTSLCTSB | |
| SCHEMBL3296361 | 0.88 | ELANE (0.41) | MCHR1 | |
| SCHEMBL3295810 | 0.82 | HTR1D (0.38) | MCHR1HRH4HTR1DHTR3AHTR6 | |
| SCHEMBL3297029 | 0.82 | HTR1D (0.38) | MCHR1HRH4HTR1DHTR3AHTR6 | |
| SCHEMBL3296134 | 0.80 | HTR1D (0.35) | MCHR1HTR1DHTR3AHTR6TMEM97 | |
| SCHEMBL3295465 | 0.80 | HTR1D (0.37) | MCHR1HRH3HTR1DHTR3AHTR6 | |
| SCHEMBL3295967 | 0.80 | TLR8 (0.34) | — | |
| SCHEMBL3294683 | 0.80 | NAPEPLD (0.36) | MCHR1HRH3CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737166-B2 | Antifungal bicyclic hetero ring compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-06-15 | — | — | US | disclosed |
| EP-1932837-A1 | BICYCLO HETEROCYCLIC COMPOUND HAVING ANTIFUNGAL ACTION | Daiichi Sankyo Company, Limited (JP) | 2008-06-18 | — | — | EP | disclosed |