Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glutaral. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL20952179 | 0.86 | HIF1A (0.44) | HIF1ATSHRMAPTTYMSALDH1A1 | |
| Glutaral SCHEMBL836 | 0.82 | — | — | |
| Glutaral SCHEMBL1285455 | 0.82 | HIF1A (1.00) | HIF1ATSHRMAPTTRPV1FAAH | |
| SCHEMBL6257489 | 0.79 | — | — | |
| Dodecanal SCHEMBL31152557 | 0.79 | TSHR (0.76) | TSHRTRPV1FAAHLPAR2LPAR3 | |
| Phosphoric Acid SCHEMBL4529450 | 0.79 | TSHR (0.76) | TSHRTRPV1FAAHLPAR2LPAR3 | |
| Glutaral SCHEMBL23631391 | 0.78 | — | — | |
| Glutaral SCHEMBL845792 | 0.78 | — | — | |
| Glutaral SCHEMBL6057369 | 0.78 | HIF1A (0.91) | HIF1ATSHRMAPTTRPV1FAAH | |
| Glutaral SCHEMBL8386286 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122038370-A | Immobilized enzyme membrane reaction system and application thereof in preparation of flaxseed oligosaccharide | 江南大学 | 2026-05-15 | — | — | CN | claimed |
| CN-119770406-B | External repairing anti-wrinkle composition and preparation method thereof | 西双版纳茶界生物科技有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119770406-A | External repairing anti-wrinkle composition and preparation method thereof | 西双版纳茶界生物科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-118169385-B | Preparation method of kit for detecting concentration of antigen by single particle capture analysis | 山东海化集团有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118162001-B | Preparation method of biological enzyme catalytic motor water suspension | 山东海化集团有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-118272472-A | Method for efficiently preparing alpha-arbutin by immobilized enzyme | 河北科技大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118225864-A | Biosensor based on monolayer self-assembled phospholipid and preparation method and application thereof | 武汉大学 | 2024-06-21 | — | — | CN | claimed |
| CN-118162001-A | Preparation method of biological enzyme catalytic motor water suspension | 山东海化集团有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-118169385-A | Preparation method of kit for detecting concentration of antigen by single particle capture analysis | 山东海化集团有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-114354722-B | Multichannel field effect transistor nano biosensor and preparation method and application thereof | 武汉大学 | 2024-06-07 | — | — | CN | claimed |
| CN-103884837-A | Method for detecting nitrofuran metabolites in animal-derived food through liquid-phase chip | SHANGHAI VETERINARY RES INST CAAS | 2014-06-25 | — | — | CN | claimed |
| CN-103822963-A | Method for identifying whether organic matters are utilized by ANAMMOX (anaerobic ammonium oxidation) bacteria in ANAMMOX reactor sludge | HARBIN INST OF TECHNOLOGY | 2014-05-28 | — | — | CN | claimed |
| CN-101592627-B | Method for manufacturing and integrating multichannel high-sensitive biosensor | SUZHOU INST NANO TECH & NANO B | 2012-12-05 | — | — | CN | claimed |
| CN-102213718-A | Heat-shrinkable combined micro-channel chip, and preparation and application method | FOURTH MILITARY MEDICAL UNIV | 2011-10-12 | — | — | CN | claimed |
| CN-101545876-B | Electron microscope observation method for sea cucumber collagen fibers in fresh and alive state | OCEAN UNIV CHINA | 2011-02-16 | — | — | CN | claimed |
| CN-101592627-A | The making integrated approach of multichannel high-sensitive biosensor | SUZHOU INST NANO TECH & NANO B (CN) | 2009-12-02 | — | — | CN | claimed |
| CN-101545876-A | Electron microscope observation method for sea cucumber collagen fibers in fresh and alive state | OCEAN UNIV CHINA | 2009-09-30 | — | — | CN | claimed |
| CN-101182507-A | Carrier and preparation and applications of immobilization lipase | UNIV NINGXIA (CN) | 2008-05-21 | — | — | CN | claimed |
| CN-2771864-Y | Protein chip for detecting blood cerebrospinal fluid pathogenic antibody | SHANDONG PROV MEDICINE BIOLOG (CN) | 2006-04-12 | — | — | CN | claimed |
| CN-1588070-A | Method for preparing multiple component biological microarray chip | UNIV NANKAI (CN) | 2005-03-02 | — | — | CN | claimed |