SCHEMBL3301460

SCHEMBL3301460

COc1ccc(C(=O)C=Cc2ccc(OCC=C(C)C)cc2)c(O)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.79
ABCG2 Q9UNQ0 6/20 0.73
APP P05067 5/20 0.73
LMNA P02545 4/20 0.73
MAPT P10636 4/20 0.73
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
CYP3A4 P08684 2/20 0.73
MAPK1 P28482 2/20 0.73
CYP2C19 P33261 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
CTSL P07711 1/20 0.67
HPGD P15428 2/20 0.66
NPC1 O15118 1/20 0.66
RECQL P46063 1/20 0.66
RAB9A P51151 1/20 0.66
ATM Q13315 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
ALDH1A1 P00352 1/20 0.66
TP53 P04637 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3301455 1.00 MAOB (0.79) MAOBABCG2APPLMNAMAPT
SCHEMBL30383772 1.00 MAOB (0.79) MAOBABCG2APPLMNAMAPT
SCHEMBL11394919 0.94 MAOB (0.89) MAOBABCG2APPLMNAMAPT
SCHEMBL11394922 0.94 MAOB (0.89) MAOBABCG2APPLMNAMAPT
SCHEMBL30384031 0.94 MAOB (0.89) MAOBABCG2APPLMNAMAPT
SCHEMBL25194697 0.92 MAOB (0.81) MAOBABCG2APPLMNAMAPT
SCHEMBL7570307 0.91 MAOB (0.87) MAOBABCG2APPLMNAMAPT
SCHEMBL30384812 0.91 MAOB (0.87) MAOBABCG2APPLMNAMAPT
SCHEMBL25198485 0.91 MAOB (0.87) MAOBABCG2APPLMNAMAPT
SCHEMBL30383474 0.88 MAOB (1.00) MAOBABCG2APPLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-8946287-B2 Chemotherapeutic flavonoids, and syntheses thereof PURDUE RESEARCH FOUNDATION (US) 2015-02-03 US disclosed
US-20100099755-A1 CHEMOTHERAPEUTIC FLAVONOIDS, AND SYNTHESES THEREOF PURDUE RESEARCH FOUNDATION (US) 2010-04-22 US disclosed
WO-2008076767-A1 CHEMOTHERAPEUTIC FLAVONOIDS, AND SYNTHESES THEREOF PURDUE RESEARCH FOUNDATION (US) 2008-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099755-A1 CHEMOTHERAPEUTIC FLAVONOIDS, AND SYNTHESES THEREOF NRAS, FAU, DPYD MAOB 277/4885ABCG2 7/4885APP 3793/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885ABCG2 3622/4885APP 1340/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885ABCG2 3622/4885APP 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.