Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303849 | 0.89 | GPR119 (0.35) | TBK1GPR119EPHX2 | |
| SCHEMBL3303406 | 0.88 | GRIK1 (0.35) | GRIK1GRIA2TBK1GPR119 | |
| SCHEMBL3306973 | 0.87 | GRIK1 (0.36) | GRIK1GRIA2TBK1GPR119IKBKE | |
| SCHEMBL3300496 | 0.86 | GRIK1 (0.40) | GRIK1GRIA2RBP4CNR2 | |
| SCHEMBL3305704 | 0.84 | GRIK1 (0.40) | GRIK1GRIA2RBP4CNR2 | |
| SCHEMBL3395793 | 0.81 | GRIK1 (0.41) | FPR2PROKR1SCN9AGRIK1GRIA2 | |
| SCHEMBL3300235 | 0.77 | GRIK1 (0.34) | GRIK1GRIA2GPR119 | |
| SCHEMBL3309302 | 0.76 | MEN1 (0.38) | GPR119 | |
| SCHEMBL3297263 | 0.76 | MEN1 (0.34) | SCN9AGRIK1GRIA2GPR119 | |
| SCHEMBL3303205 | 0.75 | SMN1; SMN2 (0.35) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | MARTINEZ-PEREZ JOSE ANTONIO | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | SLC1A2, SLC1A1, GRIN1 | FPR2 272/4885PROKR1 543/4885SCN9A 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.