Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6464634 | 0.99 | HDAC8 (0.40) | HDAC8KDM4ERAB9AALDH1A1MAPT | |
| Bromide SCHEMBL6464626 | 0.99 | HDAC8 (0.40) | HDAC8KDM4ERAB9AALDH1A1MAPT | |
| Bromide SCHEMBL6464630 | 0.87 | HDAC8 (0.40) | HDAC8KDM4ERAB9AALDH1A1MAPT | |
| Bromide SCHEMBL6464620 | 0.87 | HDAC8 (0.40) | HDAC8KDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL9144332 | 0.86 | KDM4A (0.40) | HDAC8KDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL9146632 | 0.84 | KDM4A (0.46) | HDAC8KDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL29838155 | 0.84 | HDAC8 (0.55) | HDAC8KDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL153132 | 0.84 | HDAC8 (0.55) | HDAC8KDM4ERAB9AALDH1A1MAPT | |
| Iodide SCHEMBL10938374 | 0.82 | KDM4E (0.54) | HDAC8KDM4ERAB9AALDH1A1MAPT | |
| Bromide SCHEMBL29396763 | 0.82 | HDAC8 (0.53) | HDAC8KDM4ERAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180100250-A1 | Articles Comprising an Oil Capture Polymer | THE PROCTER & GAMBLE COMPANY | 2018-04-12 | — | — | US | claimed |
| US-7737237-B2 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | PHODIA CHIMIE (FR) | 2010-06-15 | — | — | US | claimed |
| US-20060217285-A1 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | RHODIA CHIMIE (FR) | 2006-09-28 | — | — | US | claimed |
| US-4857585-A | CATIONIC ACRYLIC POLYMERS | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1989-08-15 | — | — | US | disclosed |
| US-4791161-A | CONTAINING UNSATURATED TERTIARY NITROGEN COMPOUNDS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-12-13 | — | — | US | disclosed |
| US-4528322-A | Aqueous cationic dispersions of synthetic polymers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-07-09 | — | — | US | disclosed |
| US-4525519-A | POLYMERIZATION IN AQUEOUS DISPERSION OF UNSATURATED NITROGEN COMPOUND AND CATIONIC EMULSION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-06-25 | — | — | US | disclosed |