Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | FDPS | P14324 | 10/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315723 | 0.82 | — | — | |
| SCHEMBL10936155 | 0.80 | TSHR (0.35) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL15373224 | 0.78 | TSHR (0.40) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL21472951 | 0.78 | TSHR (0.40) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL12506225 | 0.78 | TSHR (0.33) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL13825811 | 0.78 | ADRB2 (0.36) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL22903055 | 0.78 | TSHR (0.40) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL22903085 | 0.78 | TSHR (0.40) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL28312159 | 0.78 | TSHR (0.40) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL20067922 | 0.78 | TSHR (0.40) | TSHRTHRBSMPD1FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160242416-A1 | FUNGICIDAL ISOXAZOLINE CARBINOLS | DU PONT (US) | 2016-08-25 | — | — | US | disclosed |
| US-7741393-B2 | Organic silicon-based compound and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | disclosed |
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | ARSA, OR10J3, HDAC10 | TSHR 4414/4885THRB 3404/4885SMPD1 1925/4885 |
| US-20160242416-A1 | FUNGICIDAL ISOXAZOLINE CARBINOLS | CYP1B1, CHRM1, CYP1A1 | TSHR 3040/4885THRB 2499/4885SMPD1 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.