Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G6 | O60733 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | FAAH | O00519 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 1.00 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoenol Lactone SCHEMBL2060074 | 1.00 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| (S)-Bromoenol Lactone SCHEMBL3298296 | 1.00 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| (S)-Bromoenol Lactone SCHEMBL29693289 | 1.00 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| Bromoenol Lactone SCHEMBL29370529 | 1.00 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| Bromoenol Lactone SCHEMBL2060001 | 1.00 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| Bromoenol Lactone SCHEMBL2060073 | 1.00 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| Bromoenol Lactone SCHEMBL3302144 | 1.00 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL3296491 | 0.89 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL3296494 | 0.89 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL3296498 | 0.89 | PLA2G6 (1.00) | PLA2G6MAPK1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741344-B2 | Process for preparing purified S-BEL and R-BEL and compositions thereof | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2010-06-22 | — | — | US | disclosed |
| US-20050181496-A1 | Process for preparing purified s-bel and r-bel and compositions thereof | WASHINGTON UNIVERSITY | 2005-08-18 | — | — | US | disclosed |
| WO-2003079996-A2 | PROCESS FOR PREPARING PURIFIED S-BEL AND R-BEL AND COMPOSITIONS THEREOF | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2003-10-02 | — | — | WO | disclosed |