Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654856 | 1.00 | HCAR2 (0.54) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL329729 | 1.00 | HCAR2 (0.54) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL418036 | 1.00 | HCAR2 (0.54) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL11792235 | 0.98 | HCAR2 (0.56) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL345935 | 0.98 | HCAR2 (0.56) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL345936 | 0.98 | HCAR2 (0.56) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL28251620 | 0.98 | HCAR2 (0.56) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL7020452 | 0.96 | HCAR2 (0.54) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL38662185 | 0.96 | HCAR2 (0.54) | HCAR2MAPTLMNAMAPK1HTT | |
| SCHEMBL7020451 | 0.96 | HCAR2 (0.54) | HCAR2MAPTLMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041459-B1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI SPA (IT) | 2019-04-03 | — | — | EP | claimed |
| EP-3041459-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | Giuliani S.p.A. (IT) | 2016-07-13 | — | — | EP | claimed |
| WO-2015033276-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2015-03-12 | — | — | WO | claimed |
| EP-3041459-B1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI SPA (IT) | 2019-04-03 | — | — | EP | disclosed |
| EP-2384191-B1 | DIENE COMPOUNDS FOR USE IN HUMAN EPIDERMAL CELL REPAIR, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI SPA (IT) | 2018-07-18 | — | — | EP | disclosed |
| US-9597295-B2 | Diene compounds for use in human epidermal cell repair, and pharmaceutical and cosmetic compositions containing them | GIULIANI S.P.A. (IT) | 2017-03-21 | — | — | US | disclosed |
| US-9597295-B2 | Diene compounds for use in human epidermal cell repair, and pharmaceutical and cosmetic compositions containing them | GIULIANI S.P.A. (IT) | 2017-03-21 | — | — | US | disclosed |
| US-9597295-B2 | Diene compounds for use in human epidermal cell repair, and pharmaceutical and cosmetic compositions containing them | GIULIANI S.P.A. (IT) | 2017-03-21 | — | — | US | disclosed |
| EP-2593097-B1 | COMPOUNDS WITH A SKIN PIGMENTING ACTIVITY AND PHARMACEUTICAL OR COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI SPA (IT) | 2016-08-24 | — | — | EP | disclosed |
| EP-2593097-B1 | COMPOUNDS WITH A SKIN PIGMENTING ACTIVITY AND PHARMACEUTICAL OR COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI SPA (IT) | 2016-08-24 | — | — | EP | disclosed |
| US-20160213635-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2016-07-28 | — | — | US | disclosed |
| EP-2384191-A1 | DIENE COMPOUNDS FOR USE IN HUMAN EPIDERMAL CELL REPAIR, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | Giuliani S.p.A. (IT) | 2011-11-09 | — | — | EP | disclosed |
| WO-2011132177-A1 | COMPOUNDS PROVIDED WITH ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2011-10-27 | — | — | WO | disclosed |
| US-20110224298-A1 | DIENE COMPOUNDS FOR USE IN HUMAN EPIDERMAL CELL REPAIR AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2011-09-15 | — | — | US | disclosed |
| US-20110224298-A1 | DIENE COMPOUNDS FOR USE IN HUMAN EPIDERMAL CELL REPAIR AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2011-09-15 | — | — | US | disclosed |
| US-20110224298-A1 | DIENE COMPOUNDS FOR USE IN HUMAN EPIDERMAL CELL REPAIR AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2011-09-15 | — | — | US | disclosed |
| WO-2010119117-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-OCTATRIENE-1-OIC ACID AND 2,4,6-OCTATRIENE-1-OL | GIULIANI S.P.A. (IT) | 2010-10-21 | — | — | WO | disclosed |
| EP-2241543-A1 | Process for the preparation of 2,4,6-octatriene-1-oic acid and 2,4,6-octatriene-1-ol | Giuliani S.p.A. (IT) | 2010-10-20 | — | — | EP | disclosed |
| WO-2010052328-A1 | DIENE COMPOUNDS FOR USE IN HUMAN EPIDERMAL CELL REPAIR, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010052328-A1 | DIENE COMPOUNDS FOR USE IN HUMAN EPIDERMAL CELL REPAIR, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224298-A1 | DIENE COMPOUNDS FOR USE IN HUMAN EPIDERMAL CELL REPAIR AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | KRT18, CKS2, MKI67 | HCAR2 1494/4885MAPT 3855/4885LMNA 757/4885 |
| US-20160213635-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | PKLR, AKR1C3, HK1 | HCAR2 950/4885MAPT 4213/4885LMNA 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.