Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | EBP | Q15125 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tigogenin SCHEMBL12310030 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL13325468 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL14113623 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL11992492 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL14615789 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL24239067 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL14360342 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL21548986 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL22766044 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL14648706 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1762 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122005811-A | Application of IGF2BP2-m6A-VCAN-TLR2 signal shaft in preparation of medicine for treating intrahepatic bile duct cancer lymphatic metastasis | 温州医科大学附属第一医院 | 2026-05-12 | — | — | CN | claimed |
| US-20250255781-A1 | PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-08-14 | — | — | US | claimed |
| US-12296043-B2 | Liquisoft capsules | PATHEON SOFTGELS INC. (US) | 2025-05-13 | — | — | US | claimed |
| CN-119792561-A | Method for combined treatment of cancer by antibody-drug conjugate targeting Claudin18.2 | 信达生物制药(苏州)有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119632999-A | Application of sisal sapogenin in preparation of medicine for treating influenza and viral pneumonia thereof | 广州中医药大学(广州中医药研究院) | 2025-03-18 | — | — | CN | claimed |
| EP-4510999-A1 | PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS | Bristol-Myers Squibb Company (US) | 2025-02-26 | — | — | EP | claimed |
| WO-2025024478-A1 | COMPOSITIONS FOR THE MODULATION OF TASTE | IXORA SCIENTIFIC INC. (US) | 2025-01-30 | — | — | WO | claimed |
| CN-119212681-A | Method for preparing 3-D printed pharmaceutical products | 百时美施贵宝公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118308280-A | Engineering bacterium capable of being used for preparing steroid medicine intermediate by enzyme method and application thereof | 华东理工大学 | 2024-07-09 | — | — | CN | claimed |
| US-20240165020-A1 | LIQUISOFT CAPSULES | PATHEON SOFTGELS INC (US) | 2024-05-23 | — | — | US | claimed |
| CN-87100028-A | The method of direct extraction of hecogenin and tigogenin | — | 1987-09-02 | — | — | CN | claimed |
| US-4602003-A | Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia | MEDICAL RESEARCH FOUNDATION OF OREGON (US) | 1986-07-22 | — | — | US | claimed |
| US-4602005-A | Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis | MEDICAL RESEARCH FOUNDATION OF OREGON (US) | 1986-07-22 | — | — | US | claimed |
| EP-0179096-A1 | PROCESS FOR HECOGENIN PRODUCTION FROM ANAEROBIC FERMENTATION OF SISAL JUICE | UNIVERSIDADE FEDERAL DA PARAIBA (BR) | 1986-04-30 | — | — | EP | claimed |
| WO-1985005126-A1 | PROCESS FOR HECOGENIN PRODUCTION FROM ANAEROBIC FERMENTATION OF SISAL JUICE | UNIVERSIDADE FEDERAL DA PARAIBA (BR) | 1985-11-21 | — | — | WO | claimed |
| EP-0159431-A2 | Tigogenin-cellobioside and its heptaacetate, methods for their preparation, and pharmaceutical compositions containing tigogenin-cellobioside | MEDICAL RESEARCH FOUNDATION OF OREGON (US) | 1985-10-30 | — | — | EP | claimed |
| US-4265886-A | ANTIINFLAMMATORY | ROECAR HOLDINGS (NETHERLANDS ANTILLES (NV) (NL) | 1981-05-05 | — | — | US | claimed |
| US-4260603-A | Sterol glycoside with activity as prostaglandin synthetase inhibitor | HOYER GMBH & CO. KG (DE) | 1981-04-07 | — | — | US | claimed |
| US-3981867-A | ACID HYDROLYSIS, SOLVENT EXTRACTION | BEAUVOIR MAX G | 1976-09-21 | — | — | US | claimed |
| US-3935194-A | Separation of hecogenin-tigogenin mixtures | OMNI RESEARCH INCORPORATED (US) | 1976-01-27 | — | — | US | claimed |