Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | EBP | Q15125 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tigogenin SCHEMBL12310030 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL13325468 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL14113623 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL330309 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL11992492 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL14615789 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL24239067 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL21548986 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL22766044 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA | |
| Tigogenin SCHEMBL14648706 | 1.00 | KDM4E (1.00) | KDM4ESLCO1B3SLCO1B1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259837-A1 | Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-11-08 | — | — | US | disclosed |
| US-20070259837-A1 | Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259837-A1 | Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy | UTRN, MTPN, NR3C1 | KDM4E 3667/4885SLCO1B3 3668/4885SLCO1B1 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.