SCHEMBL3303650

SCHEMBL3303650

CC(C)(C)OC(=O)Nc1ccc(OC(=O)C(C)(C)Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 1/20 0.50
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
CYP17A1 P05093 2/20 0.47
GAA P10253 3/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
GLA P06280 1/20 0.45
THRB P10828 1/20 0.45
BLM P54132 1/20 0.45
CASP6 P55212 1/20 0.45
GFER P55789 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
PSMB8 P28062 1/20 0.45
NAMPT P43490 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 3/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26785207 0.91 LIPE (0.50) LIPEPPARGPPARACYP17A1GAA
SCHEMBL13592907 0.86 LIPE (0.49) LIPEPPARGPPARACYP17A1GAA
SCHEMBL23870912 0.86 LIPE (0.49) LIPEPPARGPPARACYP17A1GAA
SCHEMBL4636496 0.84 LIPE (0.52) LIPEPPARGPPARACYP17A1GAA
SCHEMBL1162988 0.84 LIPE (0.52) LIPEPPARGPPARACYP17A1GAA
SCHEMBL6665914 0.84 LIPE (0.52) LIPEPPARGPPARACYP17A1GAA
SCHEMBL13055402 0.83 CYP17A1 (0.59) LIPECYP17A1GAAPSMB8NAMPT
SCHEMBL18353040 0.83 LIPE (0.51) LIPEPPARGPPARACYP17A1GAA
SCHEMBL10025685 0.82 KMT2A (0.68) MAPTKDM4EGLATDP1MEN1
SCHEMBL29131710 0.82 HPGD (0.59) LIPEPPARGPPARACYP17A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100103358-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS ELSICON, INC. (US) 2010-04-29 US disclosed
US-20100103358-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS ELSICON, INC. (US) 2010-04-29 US disclosed
US-20100103358-A1 HYBRID POLYMER MATERIALS FOR LIQUID CRYSTAL ALIGNMENT LAYERS ELSICON, INC. (US) 2010-04-29 US disclosed
US-7632875-B2 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. (US) 2009-12-15 US disclosed
US-7632875-B2 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. (US) 2009-12-15 US disclosed
US-7632875-B2 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. (US) 2009-12-15 US disclosed
US-20060051524-A1 Hybrid polymer materials for liquid crystal alignment layers ELSICON, INC. 2006-03-09 US disclosed