Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303726 | 1.00 | S1PR1 (0.45) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| Hydrochloric Acid SCHEMBL3303966 | 0.99 | S1PR1 (0.44) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| Hydrochloric Acid SCHEMBL3303960 | 0.99 | S1PR1 (0.44) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| SCHEMBL3303906 | 0.94 | S1PR1 (0.42) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| SCHEMBL1456278 | 0.94 | S1PR1 (0.42) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| Hydrochloric Acid SCHEMBL1455819 | 0.94 | S1PR1 (0.42) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| Hydrochloric Acid SCHEMBL1645175 | 0.94 | S1PR1 (0.42) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| SCHEMBL4331697 | 0.86 | S1PR1 (0.46) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| SCHEMBL4331705 | 0.86 | S1PR1 (0.46) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 | |
| SCHEMBL5502860 | 0.84 | S1PR1 (0.47) | S1PR1SLC6A2SLC6A4SLC6A3SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053038-B1 | AMINO ALCOHOL DERIVATIVE AND IMMUNOSUPPRESSIVE AGENT HAVING SAME AS AN ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2016-10-05 | — | — | EP | claimed |
| US-20100324057-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR INFLAMMATORY BOWEL DISEASE COMPRISING AMINO ALCOHOL DERIVATIVE AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-12-23 | — | — | US | claimed |
| US-20100093745-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR DEMYELINATING DISEASE COMPRISING AMINO ALCOHOL DERIVATIVE AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-04-15 | — | — | US | claimed |
| US-20100010000-A1 | AMINO ALCOHOL DERIVATIVE AND IMMUNOSUPPRESIVE AGENT HAVING SAME AS AN ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-01-14 | — | — | US | claimed |
| EP-2053038-A1 | AMINOALCOHOL DERIVATIVE AND IMMUNOSUPPRESSANT CONTAINING THE SAME AS AN ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2009-04-29 | — | — | EP | claimed |
| EP-2053038-B1 | AMINO ALCOHOL DERIVATIVE AND IMMUNOSUPPRESSIVE AGENT HAVING SAME AS AN ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2016-10-05 | — | — | EP | disclosed |
| US-8476305-B2 | Therapeutic agent or prophylactic agent for inflammatory bowel disease comprising amino alcohol derivative as active ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| US-8273748-B2 | Amino alcohol derivative and immunosuppresive agent having same as an active ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20100324057-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR INFLAMMATORY BOWEL DISEASE COMPRISING AMINO ALCOHOL DERIVATIVE AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100093745-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR DEMYELINATING DISEASE COMPRISING AMINO ALCOHOL DERIVATIVE AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20100010000-A1 | AMINO ALCOHOL DERIVATIVE AND IMMUNOSUPPRESIVE AGENT HAVING SAME AS AN ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-2053038-A1 | AMINOALCOHOL DERIVATIVE AND IMMUNOSUPPRESSANT CONTAINING THE SAME AS AN ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324057-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR INFLAMMATORY BOWEL DISEASE COMPRISING AMINO ALCOHOL DERIVATIVE AS ACTIVE INGREDIENT | S1PR1, S1PR2, SPHK1 | S1PR1 1/4885SLC6A2 1445/4885SLC6A4 1601/4885 |
| US-20100010000-A1 | AMINO ALCOHOL DERIVATIVE AND IMMUNOSUPPRESIVE AGENT HAVING SAME AS AN ACTIVE INGREDIENT | ALDH7A1, AADAT, IDO1 | S1PR1 2503/4885SLC6A2 2082/4885SLC6A4 2151/4885 |
| US-20100093745-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR DEMYELINATING DISEASE COMPRISING AMINO ALCOHOL DERIVATIVE AS ACTIVE INGREDIENT | S1PR1, MAG, PMP22 | S1PR1 1/4885SLC6A2 1021/4885SLC6A4 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.