⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1301286 | 0.88 | — | — | |
| SCHEMBL715197 | 0.78 | — | — | |
| SCHEMBL7859766 | 0.78 | — | — | |
| SCHEMBL21596510 | 0.78 | — | — | |
| SCHEMBL6594929 | 0.78 | — | — | |
| SCHEMBL6595292 | 0.78 | — | — | |
| SCHEMBL588804 | 0.75 | — | — | |
| SCHEMBL1151226 | 0.75 | — | — | |
| Tert-Butanol SCHEMBL816081 | 0.75 | — | — | |
| Tert-Butanol SCHEMBL20503401 | 0.72 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344472-A1 | ISOQUINOLINONE DERIVATIVES | AstraZeneca AB (SE) | 2011-07-20 | — | — | EP | claimed |
| US-20100099665-A1 | ISOQUINOLINONE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-04-22 | — | — | US | claimed |
| WO-2010039079-A1 | ISOQUINOLINONE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-04-08 | — | — | WO | claimed |
| US-7115591-B2 | Pyridazinone compounds as cyclooxygenase [COX] 2 inhibitorsfor gastrointestinal disorders | ABBOTT LABORATORIES (US) | 2006-10-03 | — | — | US | claimed |
| EP-3533923-B1 | SIZING AGENT FOR CARBON FIBERS, AQUEOUS DISPERSION OF SIZING AGENT FOR CARBON FIBERS, AND SIZING AGENT-ADHERED CARBON FIBER BUNDLE | MITSUBISHI CHEM CORP (JP) | 2024-05-15 | — | — | EP | disclosed |
| US-11981686-B2 | Urea compound having substituent | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-05-14 | — | — | US | disclosed |
| CN-115232295-B | Bending-resistant polyester film and preparation method thereof | 新光合成纤维股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-11787913-B2 | Sizing agent for carbon fibers, aqueous dispersion of sizing agent for carbon fibers, and sizing agent-adhered carbon fiber bundle | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-10-17 | — | — | US | disclosed |
| US-20230058950-A1 | UREA COMPOUND HAVING SUBSTITUENT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-02-23 | — | — | US | disclosed |
| CN-115611897-A | Compounds as RSK2 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-115232295-A | Bending-resistant polyester film and preparation method thereof | 新光合成纤维股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |
| US-4448776-A | Method of using certain substituted aliphatic secondary amines or their salts for easing breathing | BUCHER KARL (CH) | 1984-05-15 | — | — | US | disclosed |
| EP-0013378-B1 | PROCESS FOR THE PRODUCTION OF RESERVE EFFECTS ON POLYESTER-CELLULOSE BLENDED TEXTILE MATERIALS | CASSELLA Aktiengesellschaft (DE) | 1982-11-17 | — | — | EP | disclosed |
| EP-0058373-A1 | Substituted aliphatic secondary amines and their salts, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-08-25 | — | — | EP | disclosed |
| US-4265629-A | Process for the production of resist effects on polyester/cellulose mixed fiber textiles | CASSELLA AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |
| US-4252530-A | USING A BASE AS DISCHARGE AGENT IN A DISCHARGE RESIST PASTE AND HEATING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| EP-0013378-A1 | Process for the production of reserve effects on polyester-cellulose blended textile materials | CASSELLA Aktiengesellschaft (DE) | 1980-07-23 | — | — | EP | disclosed |
| US-4160020-A | CELLULOSE ESTERS, CELLULOSE ETHERS | ALZA CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |