Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 5/20 | 0.61 |
| ▸ | EGFR | P00533 | 15/20 | 0.56 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331718 | 0.86 | ERBB2 (0.82) | ERBB2EGFR | |
| SCHEMBL1446399 | 0.82 | ERBB2 (0.63) | ERBB2EGFR | |
| SCHEMBL3304034 | 0.81 | EGFR (0.62) | ERBB2EGFRERBB4PDE4B | |
| SCHEMBL22282665 | 0.80 | EGFR (0.53) | ERBB2EGFRERBB4PDE4B | |
| SCHEMBL24637510 | 0.77 | ERBB2 (0.86) | ERBB2EGFR | |
| SCHEMBL185530 | 0.77 | ERBB2 (0.84) | ERBB2EGFR | |
| SCHEMBL29623469 | 0.77 | ERBB2 (0.84) | ERBB2EGFR | |
| SCHEMBL4885366 | 0.76 | ERBB2 (1.00) | ERBB2EGFRERBB4 | |
| SCHEMBL24637201 | 0.76 | ERBB2 (0.82) | ERBB2EGFR | |
| SCHEMBL4879883 | 0.75 | ERBB2 (0.81) | ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099651-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099651-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS | BDKRB2, GRK5, PRKCH | ERBB2 27/4885EGFR 63/4885ERBB4 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.