SCHEMBL3304728

SCHEMBL3304728

CCN(C)C=Nc1cc(C)c(Oc2ccc(Br)c(F)c2)cc1C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.33
KDR P35968 1/20 0.33
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3309018 1.00 EGFR (0.33) EGFRKDRHTR2ASLC6A4
SCHEMBL3304726 1.00 EGFR (0.33) EGFRKDRHTR2ASLC6A4
SCHEMBL3302325 0.91 EGFR (0.32) EGFRKDRHTR2ASLC6A4
SCHEMBL3302320 0.91 EGFR (0.32) EGFRKDRHTR2ASLC6A4
SCHEMBL3307596 0.91 HTR2A (0.32) HTR2ASLC6A4
SCHEMBL3307599 0.91 HTR2A (0.32) HTR2ASLC6A4
SCHEMBL3307303 0.90 EGFR (0.33) EGFRKDRHTR2ASLC6A4
SCHEMBL3307304 0.90 EGFR (0.33) EGFRKDRHTR2ASLC6A4
SCHEMBL3308810 0.90 HTR2A (0.41) HTR2ASLC6A4
SCHEMBL3307971 0.90 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9199922-B2 Dihalophenoxyphenylamidines and use thereof as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-01 US claimed
EP-2136627-B1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER IP GMBH (DE) 2015-05-13 EP claimed
US-20100099558-A1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-04-22 US claimed
EP-2136627-A1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES Bayer CropScience AG (DE) 2009-12-30 EP claimed
WO-2008110279-A1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-09-18 WO claimed
EP-1969933-A1 Di-halogen phenoxy phenylamidines and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP claimed
US-9199922-B2 Dihalophenoxyphenylamidines and use thereof as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-01 US disclosed
EP-2136627-B1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER IP GMBH (DE) 2015-05-13 EP disclosed
US-20100099558-A1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-04-22 US disclosed
EP-2136627-A1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES Bayer CropScience AG (DE) 2009-12-30 EP disclosed
WO-2008110279-A1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-09-18 WO disclosed
EP-1969933-A1 Di-halogen phenoxy phenylamidines and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099558-A1 DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES DDT, PAH, DNPH1 EGFR 2196/4885KDR 3490/4885HTR2A 2254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.