⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21171897 | 0.90 | — | — | |
| SCHEMBL581025 | 0.65 | — | — | |
| SCHEMBL7589478 | 0.62 | — | — | |
| SCHEMBL25626251 | 0.61 | — | — | |
| SCHEMBL9045726 | 0.60 | — | — | |
| SCHEMBL13720958 | 0.59 | — | — | |
| Ammonia Solution, Strong SCHEMBL28285952 | 0.58 | — | — | |
| SCHEMBL18676691 | 0.58 | — | — | |
| SCHEMBL13720663 | 0.58 | — | — | |
| SCHEMBL11331379 | 0.56 | CYP1A2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685344-A | 3-cyano pyrroline compound and preparation method thereof | 中国科学院福建物质结构研究所 | 2022-07-01 | — | — | CN | claimed |
| CN-104072498-A | Synthetic method for (R)-N-[5-(2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-yl]-4-(4-methyl piperazine-1-yl)benzamide | UNIV SHENYANG PHARMACEUTICAL | 2014-10-01 | — | — | CN | claimed |
| EP-0717054-A2 | Stable free radical polymerization process and thermoplastic materials produced therefrom | XEROX CORPORATION (US) | 1996-06-19 | — | — | EP | claimed |
| US-5449724-A | Stable free radical polymerization process and thermoplastic materials produced therefrom | XEROX CORPORATION (US) | 1995-09-12 | — | — | US | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| US-12201109-B2 | Method for mosquito control | DOBSON STEPHEN (US) | 2025-01-21 | — | — | US | disclosed |
| US-20230225311-A1 | Method for Mosquito Control | DOBSON STEPHEN (US) | 2023-07-20 | — | — | US | disclosed |
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-114685344-A | 3-cyano pyrroline compound and preparation method thereof | 中国科学院福建物质结构研究所 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685344-A | 3-cyano pyrroline compound and preparation method thereof | 中国科学院福建物质结构研究所 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685344-A | 3-cyano pyrroline compound and preparation method thereof | 中国科学院福建物质结构研究所 | 2022-07-01 | — | — | CN | disclosed |
| CN-107428708-B | Benzoxazine low temperature curable compositions | 亨斯迈先进材料美国有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0125684-B1 | 2-ALKYLTHIO-1-AMINOALKYL-2-PYRROLINE-3-CARBONITRILES, PROCESS FOR THEIR PREPARATION AND MEDICINES WITH ANTI-THROMBOTIC EFFECTS CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1987-07-08 | — | — | EP | disclosed |
| EP-0091045-B1 | 2-PYRROLINE-3-CARBONITRILE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1986-02-26 | — | — | EP | disclosed |
| US-4517185-A | 2-Pyrrolin-3-carbonitrile derivatives, and pharmaceutical compositions containing them and their anti-inflammatory and ulcer protective activity | WARNER-LAMBERT COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| US-4499089-A | ANTICOAGULANTS | WARNER-LAMBERT COMPANY (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0125684-A1 | 2-Alkylthio-1-aminoalkyl-2-pyrroline-3-carbonitriles, process for their preparation and medicines with anti-thrombotic effects containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1984-11-21 | — | — | EP | disclosed |
| EP-0091045-A1 | 2-Pyrroline-3-carbonitrile derivatives, process for their preparation and medicines containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1983-10-12 | — | — | EP | disclosed |