Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394761 | 1.00 | GRIK1 (0.41) | GRIK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL3393330 | 0.95 | GRIK1 (0.41) | GRIK1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL3392673 | 0.90 | GPR119 (0.39) | GRIK1GRIA2TBK1ARNR1H2 | |
| SCHEMBL3303609 | 0.90 | GPR119 (0.39) | GRIK1GRIA2TBK1ARNR1H2 | |
| SCHEMBL3395793 | 0.90 | GRIK1 (0.41) | GRIK1GRIA2TBK1ARNR1H2 | |
| SCHEMBL3395739 | 0.88 | GRIK1 (0.37) | GRIK1GRIA2ARGPR119 | |
| SCHEMBL3393487 | 0.87 | AR (0.37) | GRIK1GRIA2TBK1ARNR1H2 | |
| SCHEMBL3298914 | 0.87 | AR (0.37) | GRIK1GRIA2TBK1ARNR1H2 | |
| SCHEMBL3394767 | 0.86 | GRIK1 (0.42) | GRIK1GRIA2TBK1ARNR1H2 | |
| SCHEMBL3308660 | 0.81 | GPR119 (0.36) | GRIK1GRIA2TBK1ARGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | MARTINEZ-PEREZ JOSE ANTONIO | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | SLC1A2, SLC1A1, GRIN1 | GRIK1 8/4885CYP1A2 2346/4885POLB 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.