Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL15510580 | 0.97 | TSHR (0.32) | TSHRNAPRTTDP1 | |
| Pyrimidine SCHEMBL15510581 | 0.97 | TSHR (0.32) | TSHRNAPRTTDP1 | |
| Pyrimidine SCHEMBL15511604 | 0.97 | TSHR (0.32) | TSHRNAPRTTDP1 | |
| Pyrimidine SCHEMBL15511605 | 0.97 | TSHR (0.32) | TSHRNAPRTTDP1 | |
| Pyrimidine SCHEMBL15571740 | 0.94 | TSHR (0.30) | TSHRNAPRTTDP1 | |
| Pyrimidine SCHEMBL28020669 | 0.94 | CYP2A6 (0.33) | TSHRNAPRTTDP1CYP2A6 | |
| Pyrimidine SCHEMBL15571258 | 0.94 | TSHR (0.30) | TSHRNAPRTTDP1 | |
| Pyrimidine SCHEMBL15510547 | 0.89 | — | — | |
| Pyrimidine SCHEMBL28540377 | 0.89 | CA1 (0.32) | — | |
| Pyrimidine SCHEMBL15510413 | 0.89 | NAPRT (0.37) | NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2010-04-22 | — | — | US | claimed |
| EP-2086990-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | Centre National De La Recherche Scientifique-CNRS (FR) | 2009-08-12 | — | — | EP | claimed |
| WO-2008056264-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-05-15 | — | — | WO | claimed |
| US-8884011-B2 | Nucleotide analogues as precursor molecules for antivirals | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2014-11-11 | — | — | US | disclosed |
| US-8884011-B2 | Nucleotide analogues as precursor molecules for antivirals | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2014-11-11 | — | — | US | disclosed |
| CN-101759720-B | Acyclic nucleoside phosphonate compounds or pharmaceutically acceptable salts thereof, preparation method, application, intermediate compounds thereof, and medicinal composition containing same | SHANGHAI SINCH PHARMACEUTICALS TECHNOLOGY CO LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-101759720-B | Acyclic nucleoside phosphonate compounds or pharmaceutically acceptable salts thereof, preparation method, application, intermediate compounds thereof, and medicinal composition containing same | SHANGHAI SINCH PHARMACEUTICALS TECHNOLOGY CO LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-101759720-A | Acyclic nucleoside phosphonate compounds or pharmaceutically acceptable salts thereof, preparation method, application, intermediate compounds thereof, and medicinal composition containing same | SHANGHAI SINCH PHARMACEUTICALS | 2010-06-30 | — | — | CN | disclosed |
| CN-101759720-A | Acyclic nucleoside phosphonate compounds or pharmaceutically acceptable salts thereof, preparation method, application, intermediate compounds thereof, and medicinal composition containing same | SHANGHAI SINCH PHARMACEUTICALS | 2010-06-30 | — | — | CN | disclosed |
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2010-04-22 | — | — | US | disclosed |
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2010-04-22 | — | — | US | disclosed |
| EP-2086990-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | Centre National De La Recherche Scientifique-CNRS (FR) | 2009-08-12 | — | — | EP | disclosed |
| EP-2086990-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | Centre National De La Recherche Scientifique-CNRS (FR) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008056264-A3 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | CT NAT DE RECH SCIENT CNRS (FR) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008056264-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008056264-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | NUDT1, P2RY1, HPRT1 | TSHR 3806/4885NAPRT 226/4885TDP1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.