Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28248705 | 0.98 | TSHR (0.54) | TSHRCYP3A4PIK3CAALDH1A1TAS2R14 | |
| SCHEMBL27390124 | 0.84 | CYP3A4 (0.54) | TSHRCYP3A4PIK3CAALDH1A1CD44 | |
| SCHEMBL6630838 | 0.83 | TAS2R14 (0.46) | ALDH1A1TAS2R14MPLNOTUMTDP1 | |
| SCHEMBL8165870 | 0.83 | CYP3A4 (0.52) | TSHRCYP3A4PIK3CAALDH1A1CD44 | |
| SCHEMBL27749301 | 0.82 | ESR1 (0.43) | TSHRCYP3A4PIK3CAALDH1A1TAS2R14 | |
| SCHEMBL9016041 | 0.79 | CYP3A4 (0.48) | TSHRCYP3A4PIK3CAALDH1A1CD44 | |
| SCHEMBL8173503 | 0.79 | CYP3A4 (0.59) | TSHRCYP3A4PIK3CAALDH1A1CD44 | |
| SCHEMBL29871801 | 0.79 | CYP3A4 (0.59) | TSHRCYP3A4PIK3CAALDH1A1CD44 | |
| SCHEMBL5163816 | 0.79 | CYP3A4 (0.59) | TSHRCYP3A4PIK3CAALDH1A1CD44 | |
| SCHEMBL27277801 | 0.78 | CYP3A4 (0.46) | TSHRCYP3A4PIK3CAALDH1A1CD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710217-B | Flunixin meglumine synthesis method suitable for industrial production | 江苏恒盛药业有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-222872169-U | Reaction kettle for synthesizing 2-methyl-3-trifluoromethyl aniline | 福建盛煌生物医药科技有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119874539-A | Crystal form of 2-methyl-3-trifluoromethyl aniline and synthesis method | 福建永晶科技股份有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119707699-A | Preparation method of 2-methyl-3-trifluoromethyl aniline | 三明学院 | 2025-03-28 | — | — | CN | claimed |
| CN-115073298-B | Method for synthesizing 2-methyl-3-trifluoromethyl aniline by continuous flow microreactor | 湖南华腾制药有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-116813537-B | Preparation method and application of novel flunixin hapten | 深圳市绿诗源生物技术有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118496066-A | 1-Bromo-4-methoxy-3-methyl-2- (trifluoromethyl) benzene and preparation method thereof | 苏州汉德创宏生化科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117886700-A | Preparation method of 2-methyl-3-trifluoromethyl aniline | 福建永晶科技股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117843494-A | Method for preparing 2-methyl-3-trifluoromethyl aniline | 和鼎（南京）医药技术有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117843497-A | Method for preparing 2-methyl-3-trifluoromethyl aniline | 和鼎（南京）医药技术有限公司 | 2024-04-09 | — | — | CN | claimed |
| US-5449831-A | Process of preparing 2-methyl-3-aminobenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1995-09-12 | — | — | US | claimed |
| EP-0619809-A1 | PROCESS FOR PREPARING FLUNIXIN AND INTERMEDIATES THEREOF. | SCHERING CORP (US) | 1994-10-19 | — | — | EP | claimed |
| US-5349104-A | Base stabilized compound for heat resistance and storage stability | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-20 | — | — | US | claimed |
| EP-0568977-A2 | Stabilized aminobenzotrifluorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-10 | — | — | EP | claimed |
| WO-1993013070-A1 | PROCESS FOR PREPARING FLUNIXIN AND INTERMEDIATES THEREOF | SCHERING CORPORATION (US) | 1993-07-08 | — | — | WO | claimed |
| US-4831193-A | Synthesis of 3-amino-2-methylbenzotrifluoride | SCHERING CORPORATION (US) | 1989-05-16 | — | — | US | claimed |
| CN-1030073-A | The novel synthesis of 3-amino-2-methyl phenylfluoroform | SCHERING CORP (US) | 1989-01-04 | — | — | CN | claimed |
| WO-1988010247-A1 | NOVEL SYNTHESIS OF 3-AMINO-2-METHYLBENZOTRIFLUORIDE | SCHERING CORPORATION (US) | 1988-12-29 | — | — | WO | claimed |
| EP-0295674-A1 | Novel synthesis of 3-amino-2-methylbenzotrifluoride | SCHERING CORPORATION (US) | 1988-12-21 | — | — | EP | claimed |
| US-4209464-A | Novel synthesis of 3-amino-2-methylbenzotrifluoride from N-(2-X-5-trifluoromethylphenyl)-S,S-dimethylsulfimide | SCHERING CORPORATION (US) | 1980-06-24 | — | — | US | claimed |