Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306625 | 0.93 | KDM4E (0.59) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL7828672 | 0.83 | EGFR (0.66) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL2272671 | 0.78 | MEN1 (0.62) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL29110691 | 0.76 | MEN1 (0.82) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL28051926 | 0.76 | KDM4E (0.58) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL7203206 | 0.74 | MEN1 (0.57) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL9449427 | 0.73 | KDM4E (0.56) | KDM4ETSHRMEN1KMT2APOLB | |
| SCHEMBL11310708 | 0.73 | EGFR (0.49) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL27967619 | 0.71 | KDM4E (0.52) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL9263671 | 0.71 | MCL1 (0.61) | KDM4ETSHRMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099732-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-22 | — | — | US | disclosed |
| EP-2139855-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008113747-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099732-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNN2, KCNN1, KCNN3 | KDM4E 261/4885MAPT 1696/4885TSHR 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.