SCHEMBL330730

SCHEMBL330730

O=C=NCCSSCCN=C=S

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 10/20 0.41
MIF P14174 4/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
BACH1 O14867 1/20 0.33
MAFK O60675 1/20 0.33
EGFR P00533 1/20 0.33
PTGS2 P35354 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
NAAA Q02083 1/20 0.33
GSK3B P49841 1/20 0.32
CYP2E1 P05181 1/20 0.30
CYP2A6 P11509 1/20 0.30
HIF1A Q16665 1/20 0.30
CYP2A13 Q16696 1/20 0.30
EPAS1 Q99814 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15202 0.87
SCHEMBL1275746 0.87 TRPA1 (0.50) TRPA1MIFALDH1A1LMNATP53
SCHEMBL3916967 0.82
SCHEMBL28885494 0.80
SCHEMBL28381640 0.80 TRPA1 (0.38) TRPA1MIFALDH1A1LMNATP53
SCHEMBL7523727 0.77 TRPA1 (0.54) TRPA1MIFALDH1A1LMNATP53
SCHEMBL28344251 0.77
SCHEMBL28341605 0.77
SCHEMBL3906512 0.77 MIF (0.54) TRPA1MIFALDH1A1LMNATP53
SCHEMBL332039 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
US-20240368425-A1 Aqueous Polyurethane-Urea Dispersion COVESTRO DEUTSCHLAND AG (DE) 2024-11-07 US disclosed
EP-4396248-A1 AQUEOUS POLYURETHANE-UREA DISPERSION Covestro Deutschland AG (DE) 2024-07-10 EP disclosed
US-20240034828-A1 Aqueous Polyurethane Urea Dispersion COVESTRO DEUTSCHLAND AG (DE) 2024-02-01 US disclosed
EP-4259683-A1 AQUEOUS POLYURETHANE UREA DISPERSION Covestro Deutschland AG (DE) 2023-10-18 EP disclosed
WO-2023145981-A1 METHOD FOR PREPARING ESTER THIOL COMPOUND AND OPTICAL RESIN CONTAINING SAME 케이에스광학주식회사 2023-08-03 WO disclosed
EP-4174100-A1 AQUEOUS POLYURETHANE-UREA DISPERSION Covestro Deutschland AG (DE) 2023-05-03 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
WO-2023031029-A1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2023-03-09 WO disclosed
EP-4029894-A1 AQUEOUS POLYURETHANE UREA DISPERSION Covestro Deutschland AG (DE) 2022-07-20 EP disclosed
US-5352758-A Polythiourethane formed by reaction of specific mercaptan with polyisocyanate or polyisothiocyanate MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-04 US disclosed
EP-0351073-B1 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS (JP) 1994-09-21 EP disclosed
US-5302749-A Adding phenol to suppress yellowing and turbidity during storage MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-04-12 US disclosed
US-5283312-A Colorless, transparent, high refractive index, heat resistance, low dispersion; polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-01 US disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed