SCHEMBL330756

SCHEMBL330756

[O]c1ccc(Cl)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10780430 0.79
SCHEMBL6335819 0.78 AHR (0.70)
SCHEMBL1606861 0.77
SCHEMBL2841487 0.75
SCHEMBL330665 0.75
SCHEMBL522998 0.75
SCHEMBL5672010 0.75
SCHEMBL10487125 0.75
SCHEMBL10921883 0.75
SCHEMBL10354976 0.73 HSP90AA1 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 797 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409611-A Oxadiazole hydrazide compound and preparation method and application thereof 贵州大学 2022-04-29 CN claimed
CN-113292494-A Isoquinoline carboxylic acid compound and preparation method and application thereof 江苏苏中药业集团股份有限公司 2021-08-24 CN claimed
CN-103664972-B Diamino dihydrogen triazine derivative, its salt, preparation method, composition and application SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) 2016-02-10 CN claimed
CN-103664972-A Derivatives and salts of diamino dihydrotriazine, and preparation method, composition and application thereof SHANGHAI INST PHARM INDUSTRY 2014-03-26 CN claimed
CN-102249938-A Preparation method of 4-(2,4-dichlorophenoxy) aniline ZHEJIANG YIFAN CHEMICAL CO LTD 2011-11-23 CN claimed
US-20100130784-A1 SUBSTITUTED 1,1,1-TRIFLUORO-3-[(BENZYL)-(PYRIMIDIN-2-YL)-AMINO]-PROPAN-2-OL COMPOUNDS PFIZER INC. 2010-05-27 US claimed
US-20090105292-A9 Glucocorticoid Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2009-04-23 US claimed
US-7405221-B2 Substituted pyrimidines MERCK & CO., INC. (US) 2008-07-29 US claimed
CN-101128438-A Substituted 1,1,1-trifluoro-3-[(benzyl)-(pyrimidin-2-yl)-amino]-prop an-2-ol compounds PFIZER PROD INC (US) 2008-02-20 CN claimed
EP-1115693-B9 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO CO (US) 2007-12-19 EP claimed
WO-2000018724-A1 (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
WO-2000018723-A1 SUBSTITUTED N-ALIPHATIC-N-AROMATIC TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
WO-1999025687-A1 AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR G.D. SEARLE & CO. (US) 1999-05-27 WO claimed
EP-0861832-A1 Novel tetrahydropyridine derivatives SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI &amp; CO. LTD. (JP) 1998-09-02 EP claimed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US claimed
EP-0233801-B1 SUBSTITUTED AMIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM RHONE POULENC SANTE (FR) 1990-05-23 EP claimed
EP-0136063-B1 TRIAZOLE ANTIFUNGAL AGENTS Pfizer Limited (GB) 1990-02-07 EP claimed
US-4753941-A HYPNOTICS, MUSCLE RELAXANTS RHONE-POULENC SANTE (FR) 1988-06-28 US claimed
US-4638007-A 1-(3-SUBSTITUTED)-2-HYDROXY-2-PERFLUORO ALKYL PROPYL TRIAZOLE PFIZER INC. (US) 1987-01-20 US claimed
EP-0136063-A2 Triazole antifungal agents Pfizer Limited (GB) 1985-04-03 EP claimed