SCHEMBL33083

SCHEMBL33083

O=C(c1ccccc1)C(F)(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 1.00
MLYCD O95822 9/20 0.58
ACHE P22303 2/20 0.53
DAO P14920 1/20 0.50
TSHR P16473 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
CES2 O00748 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27672585 1.00 CES1 (1.00) CES1MLYCDACHEDAOTSHR
SCHEMBL31083855 0.97 CES1 (0.95) CES1MLYCDACHEDAOTSHR
SCHEMBL29393401 0.97 CES1 (0.95) CES1MLYCDACHEDAOTSHR
Fluoride SCHEMBL27824066 0.97 CES1 (0.95) CES1MLYCDACHEDAOTSHR
SCHEMBL10727245 0.91 CES1 (0.83) CES1MLYCDACHECES2
Acetaldehyde SCHEMBL27905428 0.89 CES1 (0.79) CES1MLYCDACHEALDH1A1
SCHEMBL4502846 0.86 CES1 (0.75) CES1MLYCD
SCHEMBL7907262 0.84 CES1 (0.73) CES1MLYCDDAOTSHRNAPRT
SCHEMBL28361767 0.84 CES1 (0.70) CES1MLYCDACHE
Piperidine SCHEMBL29259436 0.82 CES1 (0.68) CES1MLYCDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2615 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3436186-B1 POLY(ARYL PIPERIDINIUM) POLYMERS FOR USE AS HYDROXIDE EXCHANGE MEMBRANES AND IONOMERS UNIV DELAWARE (US) 2025-07-16 EP claimed
US-20250197202-A1 SYNTHESIS OF NEW POLYMERS FOR THE MANUFACTURE OF SOLID HYDROGEN TRANSFER AGENTS INSTITUTO MEXICANO DEL PETRÓLEO (MX) 2025-06-19 US claimed
CN-120137121-A Polynapadine cross-linked anion exchange membrane with hydrophilic and hydrophobic structures, and preparation method and application thereof 中国石油大学(北京) 2025-06-13 CN claimed
US-20250163224-A1 POLYMER AND PREPARATION METHOD THEREFOR, AND ANION-EXCHANGE MEMBRANE Tan Kah Kee Innovation Laboratory (CN) 2025-05-22 US claimed
US-20250163232-A1 SUBSTANCE, MEMBRANE, USE OF A MEMBRANE AND METHOD FOR THE PREPARATION OF A SUBSTANCE Forschungszentrum Jülich GmbH (DE) 2025-05-22 US claimed
US-12297327-B1 Polymer and preparation method therefor, and anion-exchange membrane Tan Kah Kee Innovation Laboratory (CN) 2025-05-13 US claimed
CN-118166376-B Membrane electrode for preparing hydrogen peroxide by oxygen reduction, preparation method thereof and membrane electrode reactor 清华大学 2025-04-01 CN claimed
CN-119529242-A Anion exchange polymer with high alkali resistance stability, anion exchange membrane, method and application 华能伊敏煤电有限责任公司 2025-02-28 CN claimed
CN-116514665-B Preparation method of (R) -2, 2-trifluoro-1-phenethylamine hydrochloride 南京优氟医药科技有限公司 2025-01-28 CN claimed
EP-4490219-A1 SUBSTANCE, MEMBRANE, USE OF A MEMBRANE, AND METHOD FOR PRODUCING A SUBSTANCE Forschungszentrum Jülich GmbH (DE) 2025-01-15 EP claimed
US-5319096-A Neuroprotective agent HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1994-06-07 US claimed
EP-0578550-A1 Process for the para-hydroxyalkylation of hydroxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1994-01-12 EP claimed
EP-0563916-A1 (1H-Indol-1-yl)-2-(amino)acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, intermediates and a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1993-10-06 EP claimed
EP-0453275-A1 Process for producing epoxy compound NIPPON OIL CO. LTD. (JP) 1991-10-23 EP claimed
EP-0155162-B1 CARBONATE SELECTIVE MEMBRANE AND ELECTRODE TECHNICON INSTRUMENTS CORPORATION (US) 1991-08-28 EP claimed
US-5013421-A Microporous tube impregnated with polymer matrix BIO-CHEM LABORATORY SYSTEMS, INC. 1991-05-07 US claimed
US-4810351-A Carbonate selective membrane and electrode TECHNICON INSTRUMENTS CORPORATION (US) 1989-03-07 US claimed
EP-0155162-A2 Carbonate selective membrane and electrode TECHNICON INSTRUMENTS CORPORATION (US) 1985-09-18 EP claimed
EP-0053767-A1 Tricyclic cytosine derivatives for use in pharmaceutical preparations and process for their preparation BAYER AG (DE) 1982-06-16 EP claimed
US-4307024-A 1,1,1-Triaryl-2,2,2-trifluoroethanes and process for their synthesis NASA 1981-12-22 US claimed