SCHEMBL330883

SCHEMBL330883

COc1ccc(C(F)(F)F)cc1N

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.70
RAB9A P51151 1/20 0.70
MAPT P10636 4/20 0.64
NPSR1 Q6W5P4 1/20 0.64
LMNA P02545 2/20 0.55
ATM Q13315 1/20 0.55
ALDH1A1 P00352 7/20 0.53
CYP3A4 P08684 1/20 0.53
CFTR P13569 1/20 0.53
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
THRB P10828 1/20 0.52
GAA P10253 2/20 0.50
HTT P42858 1/20 0.47
KDM4E B2RXH2 2/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CACNA1D Q01668 1/20 0.45
TDP1 Q9NUW8 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7165471 0.98 L3MBTL1 (0.68) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL13202230 0.87 L3MBTL1 (0.59) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL399561 0.85 L3MBTL1 (0.66) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL14380436 0.85 L3MBTL1 (0.53) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL9443798 0.85 L3MBTL1 (0.53) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL568623 0.84 L3MBTL1 (0.56) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL29811663 0.84 L3MBTL1 (0.56) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL8935331 0.83 L3MBTL1 (0.69) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL2978238 0.83 L3MBTL1 (1.00) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL24749630 0.83 L3MBTL1 (0.68) L3MBTL1RAB9AMAPTNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390612-A Preparation method and application of 1, 3-bis (2-methoxy-5- (trifluoromethyl) phenyl) urea 上海泰坦科技股份有限公司 2025-02-07 CN claimed
CN-118373778-A Preparation method of letromycin 湖北广济医药科技有限公司 2024-07-23 CN claimed
CN-117658928-A New preparation method of drug intermediate for preventing CMV infection 北京康立生医药技术开发有限公司 2024-03-08 CN claimed
CN-114539085-B Preparation of ureido derivatives 山东诚创蓝海医药科技有限公司 2023-10-20 CN claimed
CN-113880776-B Preparation method of rituximab intermediate 山东诚创蓝海医药科技有限公司 2023-06-16 CN claimed
CN-115850192-A Process for preparing 3,4-dihydroquinazoline derivatives 南京正大天晴制药有限公司 2023-03-28 CN claimed
CN-115201377-A Method for detecting migration quantity of 17 genotoxic aromatic amines in corn starch meal box food simulation liquid 扬州市食品药品检验检测中心 2022-10-18 CN claimed
CN-114539085-A Preparation of ureido derivative 山东诚创蓝海医药科技有限公司 2022-05-27 CN claimed
CN-113880776-A Preparation method of Latemozu intermediate 山东诚创蓝海医药科技有限公司 2022-01-04 CN claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
US-20050059657-A1 Aminoisoxazole derivatives active as kinase inhibitors PFIZER ITALIA S.R.L. (IT) 2005-03-17 US claimed
EP-1435948-A1 AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-07-14 EP claimed
WO-2003013517-A1 AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2003-02-20 WO claimed
US-20260083721-A1 7-CYANO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF JIANGSU YAHONG MEDITECH CO LTD (CN) 2026-03-26 US disclosed
EP-4623914-A1 USE OF 8-HYDROXYQUINOLINE DERIVATIVE Jiangsu Yahong Meditech Co., Ltd. (CN) 2025-10-01 EP disclosed
EP-0023100-A1 Herbicidal compositions comprising a diphenyl ether compound in admixture with another herbicide IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-28 EP disclosed
EP-0002041-A1 Processes for synthesizing bisazomethine-bisazo pigments CIBA-GEIGY AG (CH) 1979-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059657-A1 Aminoisoxazole derivatives active as kinase inhibitors MAP3K9, MAP3K19, MAP4K2 L3MBTL1 4176/4885RAB9A 1754/4885MAPT 281/4885
US-20260083721-A1 7-CYANO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF HCCS, SLC38A7, HRAS L3MBTL1 1152/4885RAB9A 2347/4885MAPT 4863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.