Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308234 | 0.93 | HRH3 (0.53) | HRH3 | |
| SCHEMBL3312059 | 0.91 | HRH3 (0.51) | HRH3 | |
| SCHEMBL3310089 | 0.91 | HRH3 (0.50) | HRH3 | |
| SCHEMBL3311303 | 0.89 | HRH3 (0.51) | HRH3 | |
| SCHEMBL3307505 | 0.89 | HRH3 (0.51) | HRH3KMT2AALDH1A1 | |
| SCHEMBL3309200 | 0.87 | HRH3 (0.46) | HRH3 | |
| SCHEMBL3312877 | 0.85 | HRH3 (0.50) | HRH3 | |
| SCHEMBL3306992 | 0.84 | HRH3 (0.56) | HRH3KMT2A | |
| SCHEMBL3310149 | 0.83 | HRH3 (0.58) | HRH3KMT2A | |
| SCHEMBL3315977 | 0.83 | ACKR3 (0.57) | HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113776-A1 | PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO.,LTD. (JP) | 2010-05-06 | — | — | US | claimed |
| US-20100113776-A1 | PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO.,LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113776-A1 | PYRAZOLE DERIVATIVE | HRH3, HRH4, HRH1 | HRH3 1/4885KMT2A 340/4885ALDH1A1 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.