⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846452 | 0.78 | — | — | |
| SCHEMBL5224648 | 0.78 | — | — | |
| SCHEMBL140067 | 0.78 | — | — | |
| SCHEMBL3378770 | 0.77 | — | — | |
| SCHEMBL6726103 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL22287292 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2520308 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL7663383 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL30939140 | 0.75 | — | — | |
| Tert-Butanol SCHEMBL27877025 | 0.73 | CETP (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642376-A | Polyfatty acid salt compounds for treating substrates based on fibrous amino acids, in particular hair | 迈图高新材料有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| EP-2912216-A1 | DYEABLE AND FLAME-RETARDED THERMOPLASTIC POLYURETHANE FIBERS | Lubrizol Advanced Materials, Inc. (US) | 2015-09-02 | — | — | EP | claimed |
| WO-2014066037-A1 | DYEABLE AND FLAME-RETARDED THERMOPLASTIC POLYURETHANE FIBERS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2014-05-01 | — | — | WO | claimed |
| WO-2001047911-A1 | CATIONIC AMPHIPHILES, USES AND SYNTHESIS METHOD THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2001-07-05 | — | — | WO | claimed |
| US-20250171459-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMA (US) | 2025-05-29 | — | — | US | disclosed |
| CN-119343353-A | 2-Methyl-4 ',5' -dihydrospiro [ piperidine-4, 7' -thieno [2,3-c ] pyran ] derivatives as APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4476227-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | Vertex Pharmaceuticals Incorporated (US) | 2024-12-18 | — | — | EP | disclosed |
| US-12116343-B2 | Inhibitors of APOL1 and methods of using same | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-10-15 | — | — | US | disclosed |
| CN-117642376-A | Polyfatty acid salt compounds for treating substrates based on fibrous amino acids, in particular hair | 迈图高新材料有限责任公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-114307676-B | Sulfone polymer porous liquid-stopping film and preparation method and application thereof | 杭州科百特过滤器材有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2023196410-A1 | MODIFIED NATURAL AND GREEN PARTICLES FOR COSMETIC APPLICATION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-1516084-A1 | METHOD FOR BINDING PARTICULATE, WATER-ABSORBING, ACID GROUP-CONTAINING POLYMERS TO A BASE MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003104543-A1 | METHOD FOR BINDING PARTICULATE, WATER-ABSORBING, ACID GROUP-CONTAINING POLYMERS TO A BASE MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 2003-12-18 | — | — | WO | disclosed |
| WO-2001047911-A1 | CATIONIC AMPHIPHILES, USES AND SYNTHESIS METHOD THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2001-07-05 | — | — | WO | disclosed |
| US-4820507-A | PLAQUE INHIBITORS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-04-11 | — | — | US | disclosed |
| US-4238377-A | AROMATIC HYDROCARBON RESIN, STORAGE STABILITY | CHEVRON RESEARCH COMPANY (US) | 1980-12-09 | — | — | US | disclosed |
| US-4237036-A | ADDING AN ALIPHATIC POLYAMIDE FOR STORAGE STABILITY | CHEVRON RESEARCH COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4207231-A | USED TO PRODUCE POLYURETHANE SURFACE | CHEVRON RESEARCH COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-4025683-A | SOUND-PROOFING COATING COMPOSITION | CHEVRON RESEARCH COMPANY (US) | 1977-05-24 | — | — | US | disclosed |