SCHEMBL331011

SCHEMBL331011

O=C=Nc1ccc(Sc2ccc(N=C=S)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.50
CYP3A4 P08684 5/20 0.45
P2RY6 Q15077 3/20 0.45
TSHR P16473 2/20 0.45
MIF P14174 1/20 0.45
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
TDP1 Q9NUW8 3/20 0.38
MAPK1 P28482 2/20 0.38
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
TRPA1 O75762 1/20 0.36
CYP1A2 P05177 1/20 0.34
KDM4E B2RXH2 2/20 0.33
USP2 O75604 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LTA P01374 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL484003 0.89 CYP3A4 (0.54) HSD17B10CYP3A4TSHRTDP1MAPK1
SCHEMBL484042 0.89 MIF (0.54) HSD17B10CYP3A4P2RY6TSHRMIF
SCHEMBL331404 0.87 MIF (0.56) HSD17B10CYP3A4P2RY6TSHRMIF
SCHEMBL6010323 0.82 CYP3A4 (0.44) HSD17B10CYP3A4TSHRTDP1MAPK1
SCHEMBL28491865 0.82 HSD17B10 (0.45) HSD17B10CYP3A4P2RY6TSHRMIF
SCHEMBL5954570 0.82 MIF (0.64) HSD17B10CYP3A4P2RY6MIFCA1
SCHEMBL19713006 0.82 CYP3A4 (0.47) HSD17B10CYP3A4TSHRMIFTDP1
SCHEMBL11615941 0.82 CYP3A4 (0.47) HSD17B10CYP3A4TSHRMIFTDP1
SCHEMBL13873043 0.80 NR1H2 (0.56) HSD17B10CYP3A4TSHRCA1CA2
SCHEMBL10622868 0.80 HSD17B10 (0.46) HSD17B10P2RY6MIFCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
US-20240368425-A1 Aqueous Polyurethane-Urea Dispersion COVESTRO DEUTSCHLAND AG (DE) 2024-11-07 US disclosed
EP-4396248-A1 AQUEOUS POLYURETHANE-UREA DISPERSION Covestro Deutschland AG (DE) 2024-07-10 EP disclosed
US-20240034828-A1 Aqueous Polyurethane Urea Dispersion COVESTRO DEUTSCHLAND AG (DE) 2024-02-01 US disclosed
EP-4259683-A1 AQUEOUS POLYURETHANE UREA DISPERSION Covestro Deutschland AG (DE) 2023-10-18 EP disclosed
WO-2023145981-A1 METHOD FOR PREPARING ESTER THIOL COMPOUND AND OPTICAL RESIN CONTAINING SAME 케이에스광학주식회사 2023-08-03 WO disclosed
EP-4174100-A1 AQUEOUS POLYURETHANE-UREA DISPERSION Covestro Deutschland AG (DE) 2023-05-03 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
WO-2023031029-A1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2023-03-09 WO disclosed
EP-4029894-A1 AQUEOUS POLYURETHANE UREA DISPERSION Covestro Deutschland AG (DE) 2022-07-20 EP disclosed
US-5283312-A Colorless, transparent, high refractive index, heat resistance, low dispersion; polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-01 US disclosed
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed