SCHEMBL484042

SCHEMBL484042

S=C=Nc1ccc(Sc2ccc(N=C=S)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.54
P2RY6 Q15077 3/20 0.54
HSD17B10 Q99714 3/20 0.53
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
CYP3A4 P08684 3/20 0.36
NR1H2 P55055 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
PNMT P11086 1/20 0.35
KDM4E B2RXH2 2/20 0.34
USP2 O75604 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LTA P01374 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
P2RX3 P56373 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5954570 0.91 MIF (0.64) MIFP2RY6HSD17B10CA1CA2
SCHEMBL10622884 0.89 MAOA (0.47) MIFP2RY6HSD17B10CA1CA2
SCHEMBL10622868 0.89 HSD17B10 (0.46) MIFP2RY6HSD17B10CA1CA2
SCHEMBL331011 0.89 HSD17B10 (0.50) MIFP2RY6HSD17B10CA1CA2
SCHEMBL6211797 0.88 DDAH1 (0.54) MIFP2RY6HSD17B10CA1CA2
SCHEMBL10622883 0.86 MAOB (0.55) MIFP2RY6HSD17B10CA1CA2
SCHEMBL483870 0.85 MIF (0.54) MIFP2RY6HSD17B10CA1CA2
SCHEMBL10625623 0.84 HSD17B10 (0.42) MIFP2RY6HSD17B10CA1CA2
Bitoscanate SCHEMBL157128 0.84 MIF (0.72) MIFP2RY6HSD17B10CA1CA2
SCHEMBL10622842 0.82 MAPT (0.54) MIFP2RY6HSD17B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748866-A1 AQUEOUS POLYURETHANE DISPERSIONS AND APPLICATIONS THEREOF Covestro Deutschland AG (DE) 2026-05-27 EP disclosed
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
EP-3841141-B1 A COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF COVESTRO DEUTSCHLAND AG (DE) 2025-01-01 EP disclosed
US-20240368425-A1 Aqueous Polyurethane-Urea Dispersion COVESTRO DEUTSCHLAND AG (DE) 2024-11-07 US disclosed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
EP-4396248-A1 AQUEOUS POLYURETHANE-UREA DISPERSION Covestro Deutschland AG (DE) 2024-07-10 EP disclosed
US-11965108-B2 Composition, preparation method and application thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
US-11965092-B2 Polyurethane composition, preparation method and application thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
CN-117897424-A Aqueous polyurethane urea dispersions 科思创德国股份有限公司 2024-04-16 CN disclosed
US-20240034828-A1 Aqueous Polyurethane Urea Dispersion COVESTRO DEUTSCHLAND AG (DE) 2024-02-01 US disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
US-4771062-A ENZYME INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1988-09-13 US disclosed
EP-0240680-A1 Diaryl sulfide derivatives BAYER AG (DE) 1987-10-14 EP disclosed