Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.84 |
| ▸ | CA9 | Q16790 | 1/20 | 0.84 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | PARP1 | P09874 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | CASP6 | P55212 | 2/20 | 0.55 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | CASP9 | P55211 | 1/20 | 0.55 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.51 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818277 | 0.92 | CA12 (1.00) | CA12CA9GSK3BPARP1CASP3 | |
| SCHEMBL14896 | 0.92 | CA12 (1.00) | CA12CA9GSK3BPARP1CASP3 | |
| SCHEMBL29355184 | 0.92 | CA12 (1.00) | CA12CA9GSK3BPARP1CASP3 | |
| SCHEMBL8213866 | 0.90 | CA12 (0.95) | CA12CA9GSK3BPARP1CASP3 | |
| SCHEMBL8213864 | 0.90 | CA12 (0.95) | CA12CA9GSK3BPARP1CASP3 | |
| Water SCHEMBL19462703 | 0.90 | CA12 (0.95) | CA12CA9GSK3BPARP1CASP3 | |
| Hydrochloric Acid SCHEMBL5046932 | 0.90 | CA12 (0.95) | CA12CA9GSK3BPARP1CASP3 | |
| Water SCHEMBL19462706 | 0.90 | CA12 (0.95) | CA12CA9GSK3BPARP1CASP3 | |
| SCHEMBL11354047 | 0.90 | CA12 (0.95) | CA12CA9GSK3BPARP1CASP3 | |
| Water SCHEMBL19462837 | 0.90 | CA12 (0.95) | CA12CA9GSK3BPARP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2543390-A1 | Pharmaceutical composition | Kyowa Hakko Kirin Co., Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-20100098690-A1 | PHARMACEUTICAL COMPOSITION | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2133094-A1 | PHARMACEUTICAL COMPOSITION | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098690-A1 | PHARMACEUTICAL COMPOSITION | HSP90B1, HSP90AB1, HSP90AB2P | CA12 4173/4885CA9 3289/4885GSK3B 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.