Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245483 | 0.92 | PSIP1 (0.40) | PSIP1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL3300974 | 0.92 | PSIP1 (0.40) | PSIP1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL245279 | 0.92 | PSIP1 (0.42) | PSIP1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL3321821 | 0.87 | PSIP1 (0.44) | PSIP1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL3298653 | 0.83 | PSIP1 (0.34) | PSIP1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL10283942 | 0.83 | PSIP1 (0.34) | PSIP1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL3300978 | 0.82 | PSIP1 (0.39) | PSIP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL243592 | 0.82 | PSIP1 (0.41) | PSIP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL243591 | 0.82 | PSIP1 (0.41) | PSIP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3298740 | 0.82 | PSIP1 (0.39) | PSIP1KDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003498-A1 | 2 -QUINOLINYL- ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |