Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzododecinium SCHEMBL330702 | 1.00 | DNM1 (0.67) | DNM1MEN1KMT2AMAPK1TP53 | |
| Cetalkonium SCHEMBL10808292 | 1.00 | DNM1 (0.67) | DNM1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL331209 | 1.00 | DNM1 (0.67) | DNM1MEN1KMT2AMAPK1TP53 | |
| Benzododecinium SCHEMBL330679 | 0.93 | DNM1 (0.72) | DNM1MEN1KMT2AMAPK1TP53 | |
| Cetalkonium SCHEMBL27930689 | 0.93 | DNM1 (0.72) | DNM1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL331113 | 0.93 | DNM1 (0.72) | DNM1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL332021 | 0.93 | DNM1 (0.72) | DNM1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL9494526 | 0.89 | DNM1 (0.65) | DNM1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL10542969 | 0.89 | HTT (0.57) | DNM1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL11134789 | 0.89 | HTT (0.60) | DNM1MEN1KMT2AMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385504-B1 | Heat-latent curing catalyst and resin compositions containing the same | NIPPON PAINT CO LTD (JP) | 1995-10-04 | — | — | EP | claimed |
| EP-0315084-B1 | METHOD FOR INCREASING THE ELECTROSTATIC CHARGEABILITY OF POWDER VARNISHES OR POWDERS, AND THEIR USE IN THE SURFACE COATING OF SOLID OBJECTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | claimed |
| US-RE32883-E | Quarternary ammonium sulfate or sulfonate charge control agents for electrophotographic developers compatible with viton fuser | XEROX CORPORATION (US) | 1989-03-07 | — | — | US | claimed |
| US-4338390-A | Quarternary ammonium sulfate or sulfonate charge control agents for electrophotographic developers compatible with viton fuser | XEROX CORPORATION (US) | 1982-07-06 | — | — | US | claimed |
| EP-2295484-B1 | POLYMERIZABLE COMPOSITION FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYTHIOURETHANE OPTICAL MATERIAL OBTAINED FROM SAME POLYMERIZABLE COMPOSITION, AND POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL | MITSUI CHEMICALS INC (JP) | 2018-01-17 | — | — | EP | disclosed |
| EP-2407498-B1 | Polymerizable composition for polythiourethane optical material, polythiourethane optical material obtained from the polymerizable composition, and polymerization catalyst for polythiourethane optical material | MITSUI CHEMICALS INC (JP) | 2017-11-15 | — | — | EP | disclosed |
| US-9176403-B2 | Process for preparing latex comprising charge control agent | XEROX CORPORATION (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150024323-A1 | PROCESS FOR PREPARING LATEX COMPRISING CHARGE CONTROL AGENT | XEROX CORPORATION | 2015-01-22 | — | — | US | disclosed |
| US-8900787-B2 | Toner compositions | XEROX CORPORATION (US) | 2014-12-02 | — | — | US | disclosed |
| US-20130252162-A1 | TONER COMPOSITIONS | XEROX CORPORATION (US) | 2013-09-26 | — | — | US | disclosed |
| US-8304507-B2 | Polymerizable composition for polythiourethane optical material, polythiourethane optical material obtained from the polymerizable composition, and polymerization catalyst for polythiourethane optical material | MITSUI CHEMICALS, INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| EP-2407498-A2 | Polymerizable composition for polythiourethane optical material, polythiourethane optical material obtained from the polymerizable composition, and polymerization catalyst for polythiourethane optical material | Mitsui Chemicals, Inc. (JP) | 2012-01-18 | — | — | EP | disclosed |
| EP-0321363-A2 | New electrostatographic toners and developers containing new charge-control agents | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-06-21 | — | — | EP | disclosed |
| US-4826749-A | QUATERNARY AMMONIUM SALT | ORIENT CHEMICAL INDUSTRIES LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-RE32883-E | Quarternary ammonium sulfate or sulfonate charge control agents for electrophotographic developers compatible with viton fuser | XEROX CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0242420-A1 | A toner for developing electrostatic latent images and a use thereof | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |
| US-4654175-A | QUATERNARY AMMONIUM, CHARGING, ELECTROGRAPHY, DEVELOPERS | XEROX CORPORATION (US) | 1987-03-31 | — | — | US | disclosed |
| US-4480023-A | Radiant assist pressure fixing process with polyamide toner compositions | XEROX CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4338390-A | Quarternary ammonium sulfate or sulfonate charge control agents for electrophotographic developers compatible with viton fuser | XEROX CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0053888-A2 | Electrostatic toner composition | XEROX CORPORATION (US) | 1982-06-16 | — | — | EP | disclosed |